[11] Colo Colo 4-1 Universidad de Chile [9] 2022-03-06 15:00
Stadium: Monumental David Arellano Round: 5
Referee: Roberto Andres Tobar Vargas Home Manager: Gustavo Quinteros Away Manager: Santiago Escobar
Head to Head
| Club Friendly List | 2022/01/15 00:00 | Colo Colo v Universidad de Chile | W | 2-1 |
| Chile Primera Division | 2021/09/26 19:30 | Universidad de Chile v Colo Colo | W | 1-3 |
| Chile Primera Division | 2021/04/25 20:00 | Colo Colo v Universidad de Chile | W | 1-0 |
| Chile Primera Division | 2021/01/17 21:00 | Colo Colo v Universidad de Chile | D | 0-0 |
| Chile Primera Division | 2020/09/06 17:00 | Universidad de Chile v Colo Colo | D | 1-1 |
| Chile Cup | 2020/01/22 21:30 | Universidad de Chile v Colo Colo | W | 1-2 |
| Chile Primera Division | 2019/10/05 18:00 | Colo Colo v Universidad de Chile | W | 3-2 |
| Chile Primera Division | 2019/05/18 16:00 | Universidad de Chile v Colo Colo | D | 1-1 |
Home History
| Chile Primera Division | 2022/02/27 15:00 | Huachipato v Colo Colo | L | 1-0 |
| Chile Primera Division | 2022/02/19 21:00 | Colo Colo v Audax Italiano | D | 1-1 |
| Chile Primera Division | 2022/02/13 21:00 | La Serena v Colo Colo | D | 1-1 |
| Chile Primera Division | 2022/02/06 23:30 | Colo Colo v Everton de Vina | W | 2-0 |
| Chile Super Cup | 2022/01/23 22:00 | Universidad Catolica v Colo Colo | W | 0-2 |
| Club Friendly List | 2022/01/18 00:00 | Boca Juniors v Colo Colo | L | 2-0 |
| Club Friendly List | 2022/01/15 00:00 | Colo Colo v Universidad de Chile | W | 2-1 |
| Chile Primera Division | 2021/12/04 21:00 | CD Antofagasta v Colo Colo | L | 1-0 |
Away History
| Chile Primera Division | 2022/02/28 23:30 | Universidad de Chile v O'Higgins | L | 0-1 |
| Chile Primera Division | 2022/02/21 21:00 | Nublense v Universidad de Chile | L | 3-2 |
| Chile Primera Division | 2022/02/12 23:30 | Universidad de Chile v CD Antofagasta | W | 2-1 |
| Chile Primera Division | 2022/02/06 21:00 | Union La Calera v Universidad de Chile | W | 2-4 |
| Club Friendly List | 2022/01/22 00:15 | Boca Juniors v Universidad de Chile | L | 3-2 |
| Club Friendly List | 2022/01/15 00:00 | Colo Colo v Universidad de Chile | L | 2-1 |
| Chile Primera Division | 2021/12/05 21:00 | Universidad de Chile v Union La Calera | W | 3-2 |
| Chile Primera Division | 2021/11/27 21:00 | Cobresal v Universidad de Chile | D | 0-0 |