[6] DET Red Wings 4-3 TB Lightning [3] 2022-04-19 23:00
Stadium: Amalie Arena
Home Manager: Jon Cooper Away Manager: Jeff Blashill
Head to Head
| NHL | 2022/03/26 16:30 | TB Lightning v DET Red Wings | L | 2-1 |
| NHL | 2022/03/05 00:00 | DET Red Wings v TB Lightning | L | 1-3 |
| NHL | 2021/10/14 23:30 | TB Lightning v DET Red Wings | L | 7-6 |
| NHL | 2021/05/02 19:00 | TB Lightning v DET Red Wings | L | 2-1 |
| NHL | 2021/05/01 19:00 | TB Lightning v DET Red Wings | W | 0-1 |
| NHL | 2021/04/04 16:00 | DET Red Wings v TB Lightning | W | 5-1 |
| NHL | 2021/04/03 17:00 | DET Red Wings v TB Lightning | L | 1-2 |
| NHL | 2021/03/12 00:30 | TB Lightning v DET Red Wings | W | 4-6 |
Home History
| NHL | 2022/04/17 17:00 | FLA Panthers v DET Red Wings | L | 6-1 |
| NHL | 2022/04/16 16:30 | DET Red Wings v NY Rangers | L | 0-4 |
| NHL | 2022/04/14 23:00 | DET Red Wings v CAR Hurricanes | W | 3-0 |
| NHL | 2022/04/12 23:30 | OTT Senators v DET Red Wings | L | 4-1 |
| NHL | 2022/04/09 23:00 | CLB Blue Jackets v DET Red Wings | L | 5-4 |
| NHL | 2022/04/06 23:30 | DET Red Wings v WIN Jets | W | 3-1 |
| NHL | 2022/04/05 23:30 | BOS Bruins v DET Red Wings | W | 3-5 |
| NHL | 2022/04/03 17:00 | DET Red Wings v OTT Senators | L | 2-5 |
Away History
| NHL | 2022/04/16 23:00 | WIN Jets v TB Lightning | W | 4-7 |
| NHL | 2022/04/14 23:00 | ANA Ducks v TB Lightning | W | 3-4 |
| NHL | 2022/04/13 01:30 | TB Lightning v DAL Stars | L | 0-1 |
| NHL | 2022/04/10 21:00 | BUF Sabres v TB Lightning | W | 0-5 |
| NHL | 2022/04/08 23:00 | BOS Bruins v TB Lightning | L | 2-1 |
| NHL | 2022/04/06 23:30 | TB Lightning v WAS Capitals | L | 3-4 |
| NHL | 2022/04/04 23:30 | TOR Maple Leafs v TB Lightning | L | 6-2 |
| NHL | 2022/04/02 23:00 | MON Canadiens v TB Lightning | L | 5-4 |