Head to Head
| Bolivia Apertura | 2021/09/27 19:00 | Real Santa Cruz v Guabira | W | 3-0 |
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | L | 1-0 |
Home History
| Bolivia Apertura | 2022/02/06 16:00 | Real Santa Cruz v Universitario de Sucre | L | 0-1 |
| America Friendlies | 2022/01/27 21:21 | Royal Pari FC v Real Santa Cruz | D | 1-1 |
| America Friendlies | 2022/01/23 21:00 | Royal Pari FC v Real Santa Cruz | L | 3-1 |
| Bolivia Apertura | 2021/12/12 19:00 | Real Santa Cruz v The Strongest | W | 1-0 |
| Bolivia Apertura | 2021/12/05 00:30 | Oriente Petrolero v Real Santa Cruz | L | 2-0 |
| Bolivia Apertura | 2021/12/01 19:00 | Real Santa Cruz v Nacional Potosi | D | 1-1 |
| Bolivia Apertura | 2021/11/27 23:30 | Independiente Petrolero v Real Santa Cruz | L | 2-1 |
| Bolivia Clausura | 2021/11/22 19:45 | San Jose v Real Santa Cruz | W | 1-2 |
Away History
| Bolivia Apertura | 2022/02/06 19:00 | Club Aurora v Guabira | D | 0-0 |
| Bolivia Apertura | 2021/12/12 19:00 | Guabira v Independiente Petrolero | L | 2-3 |
| Bolivia Apertura | 2021/12/05 19:00 | Real Potosi v Guabira | W | 1-3 |
| Bolivia Apertura | 2021/12/02 19:00 | Guabira v Royal Pari FC | W | 3-2 |
| Bolivia Apertura | 2021/11/27 19:00 | Always Ready v Guabira | L | 6-1 |
| Bolivia Apertura | 2021/11/20 19:00 | Guabira v Atletico Palmaflor Vinto | W | 2-0 |
| Bolivia Apertura | 2021/10/30 21:15 | Jorge Wilstermann v Guabira | L | 2-1 |
| Bolivia Apertura | 2021/10/26 19:00 | Guabira v The Strongest | D | 0-0 |