[7] Real Santa Cruz 1-2 The Strongest [1] 2022-02-26 19:00
Stadium: Estadio Juan Carlos Duran Round: 4
Head to Head
| Bolivia Apertura | 2021/12/12 19:00 | Real Santa Cruz v The Strongest | W | 1-0 |
| Bolivia Apertura | 2021/08/14 23:30 | The Strongest v Real Santa Cruz | W | 1-2 |
| Bolivia Apertura | 2020/12/02 23:00 | The Strongest v Real Santa Cruz | L | 4-2 |
| Bolivia Apertura | 2020/01/27 01:00 | Real Santa Cruz v The Strongest | W | 3-2 |
Home History
| Bolivia Apertura | 2022/02/18 21:15 | Nacional Potosi v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2022/02/13 19:00 | Real Santa Cruz v Guabira | D | 2-2 |
| Bolivia Apertura | 2022/02/06 16:00 | Real Santa Cruz v Universitario de Sucre | L | 0-1 |
| America Friendlies | 2022/01/27 21:21 | Royal Pari FC v Real Santa Cruz | D | 1-1 |
| America Friendlies | 2022/01/23 21:00 | Royal Pari FC v Real Santa Cruz | L | 3-1 |
| Bolivia Apertura | 2021/12/12 19:00 | Real Santa Cruz v The Strongest | W | 1-0 |
| Bolivia Apertura | 2021/12/05 00:30 | Oriente Petrolero v Real Santa Cruz | L | 2-0 |
| Bolivia Apertura | 2021/12/01 19:00 | Real Santa Cruz v Nacional Potosi | D | 1-1 |
Away History
| Copa Libertadores Qualification | 2022/02/23 00:30 | Plaza Colonia v The Strongest | L | 2-0 |
| Bolivia Apertura | 2022/02/18 23:30 | The Strongest v Universitario de Sucre | D | 1-1 |
| Bolivia Apertura | 2022/02/13 16:00 | Atletico Palmaflor Vinto v The Strongest | W | 0-3 |
| Bolivia Apertura | 2022/02/06 21:15 | The Strongest v Oriente Petrolero | W | 2-0 |
| Bolivia Apertura | 2021/12/12 19:00 | Real Santa Cruz v The Strongest | L | 1-0 |
| Bolivia Clausura | 2021/12/05 19:00 | The Strongest v San Jose | W | 2-0 |
| Bolivia Apertura | 2021/12/03 00:00 | Real Tomayapo v The Strongest | D | 0-0 |
| Bolivia Apertura | 2021/11/26 22:15 | The Strongest v Club Aurora | W | 3-0 |