Stadium: Sam M. Vadalabene Center
Home Manager: Brian Barone Away Manager: Marty Simmons
| NCAAB | 2022/01/14 02:00 | SIU Edwardsville v Eastern Illinois | L | 66-53 |
| NCAAB | 2021/02/02 23:00 | Eastern Illinois v SIU Edwardsville | W | 70-61 |
| NCAAB | 2021/01/27 01:00 | SIU Edwardsville v Eastern Illinois | L | 87-74 |
| NCAAB | 2020/02/29 20:00 | Eastern Illinois v SIU Edwardsville | W | 70-52 |
| NCAAB | 2020/02/14 01:30 | SIU Edwardsville v Eastern Illinois | L | 76-74 |
| NCAAB | 2019/02/14 23:30 | Eastern Illinois v SIU Edwardsville | W | 79-65 |
| NCAAB | 2019/01/05 21:15 | SIU Edwardsville v Eastern Illinois | W | 81-84 |
| NCAAB | 2018/02/24 21:15 | SIU Edwardsville v Eastern Illinois | W | 56-68 |
| NCAAB | 2022/02/19 21:00 | Eastern Illinois v Tennessee State | L | 49-63 |
| NCAAB | 2022/02/18 01:00 | Eastern Illinois v Belmont | L | 57-81 |
| NCAAB | 2022/02/14 23:00 | Eastern Illinois v Austin Peay | L | 54-62 |
| NCAAB | 2022/02/12 21:30 | Tennessee Martin v Eastern Illinois | W | 70-82 |
| NCAAB | 2022/02/11 01:30 | Tennessee Tech v Eastern Illinois | L | 73-62 |
| NCAAB | 2022/02/08 00:00 | Eastern Illinois v Tennessee Tech | L | 58-84 |
| NCAAB | 2022/02/05 22:00 | Eastern Illinois v SE Missouri State | L | 56-63 |
| NCAAB | 2022/01/29 21:30 | Tennessee State v Eastern Illinois | W | 57-62 |
| NCAAB | 2022/02/19 22:00 | SIU Edwardsville v Belmont | L | 62-73 |
| NCAAB | 2022/02/18 01:30 | SIU Edwardsville v Tennessee State | L | 65-81 |
| NCAAB | 2022/02/12 21:30 | Tennessee Tech v SIU Edwardsville | W | 60-61 |
| NCAAB | 2022/02/11 01:30 | Tennessee Martin v SIU Edwardsville | W | 63-71 |
| NCAAB | 2022/02/08 02:00 | SE Missouri State v SIU Edwardsville | L | 76-47 |
| NCAAB | 2022/02/06 01:00 | SIU Edwardsville v Murray State | L | 59-79 |
| NCAAB | 2022/02/01 00:00 | SIU Edwardsville v Austin Peay | L | 63-68 |
| NCAAB | 2022/01/29 22:00 | SIU Edwardsville v SE Missouri State | L | 77-85 |