[101] Kevin Anderson 6-7,7-6,6-7 John Isner [26] 2022-02-10 01:00
Stadium: Stadium Round: 26 Ground: Hardcourt indoor
Head to Head
| Wimbledon | 2018/07/13 12:00 | Kevin Anderson v John Isner | 7-6,6-7,6-7,6-4,26-24 |
| ATP Cincinnati | 2014/08/12 00:45 | Kevin Anderson v John Isner | 3-6,4-6 |
Home History
| ATP Dallas | 2022/02/07 22:00 | Kevin Anderson v Sam Querrey | 6-4,6-4 |
| Australian Open | 2022/01/17 07:45 | Reilly Opelka v Kevin Anderson | 6-3,6-4,7-6 |
| ATP Melbourne | 2022/01/05 08:00 | Jaume Munar v Kevin Anderson | 6-4,6-4 |
| ATP Paris | 2021/10/30 10:05 | Kevin Anderson v Hugo Gaston | 6-7,6-2,6-7 |
| ATP Vienna | 2021/10/25 14:55 | Alex De Minaur v Kevin Anderson | 6-3,7-6 |
| ATP Vienna | 2021/10/24 13:20 | Kevin Anderson v Roberto Carballes Baena | 7-5,4-6,7-6 |
| ATP Vienna | 2021/10/23 15:15 | Kevin Anderson v Jurij Rodionov | 6-1,6-4 |
| ATP Indian Wells | 2021/10/13 01:00 | Gael Monfils v Kevin Anderson | 7-5,6-2 |
Away History
| Australian Open | 2022/01/18 03:15 | Maxime Cressy v John Isner | 7-6,7-5,6-7,6-7,6-4 |
| ATP Adelaide 2 | 2022/01/12 04:30 | Thanasi Kokkinakis v John Isner | 6-7,7-6,7-6 |
| ATP Cup | 2022/01/05 23:00 | Daniel Evans v John Isner | 6-4,7-6 |
| ATP Cup | 2022/01/03 23:00 | Jan-Lennard Struff v John Isner | 7-6,4-6,7-5 |
| ATP Cup | 2022/01/01 23:00 | Brayden Schnur v John Isner | 1-6,3-6 |
| Davis Cup | 2021/11/28 19:10 | John Isner v Daniel Elahi Galan | 3-6,6-3,6-7 |
| Davis Cup | 2021/11/26 16:45 | John Isner v Jannik Sinner | 2-6,0-6 |
| ATP Indian Wells | 2021/10/11 03:30 | John Isner v Yoshihito Nishioka | 6-3,6-4 |