Head to Head
| USA USL Championship | 2021/05/22 23:30 | Louisville City FC v San Diego Loyal | L | 2-1 |
Home History
| USA USL Championship | 2022/04/14 02:00 | Oakland Roots v San Diego Loyal | D | 2-2 |
| USA USL Championship | 2022/04/10 02:00 | San Diego Loyal v Charleston Battery | W | 4-1 |
| USA US Open Cup | 2022/04/07 02:30 | Albion San Diego v San Diego Loyal | W | 1-2 |
| USA USL Championship | 2022/04/03 21:00 | San Diego Loyal v El Paso Locomotive FC | W | 3-2 |
| USA USL Championship | 2022/03/27 02:30 | Phoenix Rising FC v San Diego Loyal | W | 2-3 |
| USA USL Championship | 2022/03/24 00:30 | Tulsa v San Diego Loyal | L | 1-0 |
| USA USL Championship | 2022/03/20 02:00 | San Diego Loyal v Sacramento Republic | W | 2-0 |
| USA USL Championship | 2022/03/13 03:00 | San Diego Loyal v Ventura County FC | W | 2-1 |
Away History
| USA USL Championship | 2022/04/10 20:00 | Loudoun United FC v Louisville City FC | W | 0-2 |
| USA US Open Cup | 2022/04/06 23:30 | Louisville City FC v Chattanooga Red Wolves | W | 1-0 |
| USA USL Championship | 2022/04/02 23:30 | Birmingham Legion FC v Louisville City FC | D | 0-0 |
| USA USL Championship | 2022/03/26 23:30 | Louisville City FC v Indy Eleven | D | 1-1 |
| USA USL Championship | 2022/03/23 23:00 | New York Red Bulls II v Louisville City FC | W | 0-2 |
| USA USL Championship | 2022/03/19 23:30 | Louisville City FC v Miami FC | W | 2-0 |
| USA USL Championship | 2022/03/13 00:30 | Louisville City FC v Atlanta United II | W | 1-0 |
| Club Friendly List | 2022/02/16 19:00 | Louisville City FC v El Paso Locomotive FC | W | 5-2 |