[2] Cerro Porteno 0-0 Guairena FC [9] 2022-05-12 00:15
Stadium: General Pablo Rojas Round: 15
Referee: Derlis Lopez Home Manager: Francisco Arce Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay Division Profesional | 2022/02/27 21:00 | Guairena FC v Cerro Porteno | W | 0-2 |
| Paraguay Division Profesional | 2021/10/25 21:30 | Guairena FC v Cerro Porteno | W | 0-2 |
| Paraguay Division Profesional | 2021/08/07 23:30 | Cerro Porteno v Guairena FC | W | 2-0 |
| Paraguay Division Profesional | 2021/04/25 21:45 | Guairena FC v Cerro Porteno | W | 0-1 |
| Paraguay Division Profesional | 2021/02/21 21:30 | Cerro Porteno v Guairena FC | D | 2-2 |
| Paraguay Division Profesional | 2020/11/07 21:15 | Guairena FC v Cerro Porteno | D | 1-1 |
| Paraguay Division Profesional | 2020/08/26 21:00 | Guairena FC v Cerro Porteno | W | 1-2 |
| Paraguay Division Profesional | 2020/02/15 22:15 | Cerro Porteno v Guairena FC | D | 2-2 |
Home History
| Paraguay Division Profesional | 2022/05/08 23:15 | Guarani Asuncion v Cerro Porteno | W | 1-2 |
| Copa Libertadores | 2022/05/04 22:00 | Colon v Cerro Porteno | L | 2-1 |
| Paraguay Division Profesional | 2022/04/30 23:45 | Cerro Porteno v Nacional Asuncion | W | 1-0 |
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteno v Penarol | W | 1-0 |
| Paraguay Division Profesional | 2022/04/24 21:30 | Sportivo Ameliano v Cerro Porteno | W | 0-1 |
| Paraguay Division Profesional | 2022/04/21 22:00 | Tacuary v Cerro Porteno | L | 2-0 |
| Paraguay Division Profesional | 2022/04/17 22:00 | Cerro Porteno v Libertad Asuncion | W | 4-0 |
| Copa Libertadores | 2022/04/12 22:15 | Cerro Porteno v Colon | W | 3-1 |
Away History
| Paraguay Division Profesional | 2022/05/08 21:00 | Guairena FC v Sol de America | W | 2-1 |
| Copa Sudamericana | 2022/05/05 22:15 | Guairena FC v Internacional | D | 1-1 |
| Paraguay Division Profesional | 2022/05/01 23:15 | Olimpia Asuncion v Guairena FC | L | 1-0 |
| Copa Sudamericana | 2022/04/27 22:15 | Guairena FC v Club 9 de Octubre | W | 1-0 |
| Paraguay Division Profesional | 2022/04/24 23:45 | Guarani Asuncion v Guairena FC | L | 2-1 |
| Paraguay Division Profesional | 2022/04/20 22:00 | Nacional Asuncion v Guairena FC | L | 3-1 |
| Paraguay Division Profesional | 2022/04/17 19:45 | Guairena FC v Sportivo Ameliano | W | 2-1 |
| Copa Sudamericana | 2022/04/15 00:30 | Internacional v Guairena FC | D | 1-1 |