[13] Club Deportes Santa Cruz 2-1 Melipilla [16] 2022-10-24 21:00
Stadium: Estadio Municipal Joaquín Muñoz García Round: 33
Head to Head
| Chile Primera B | 2022/05/22 21:30 | Melipilla v Club Deportes Santa Cruz | L | 1-0 |
| Chile Primera B | 2020/12/23 23:30 | Melipilla v Club Deportes Santa Cruz | D | 0-0 |
| Chile Primera B | 2020/08/31 19:00 | Club Deportes Santa Cruz v Melipilla | L | 2-4 |
| Chile Primera B | 2019/09/29 20:00 | Melipilla v Club Deportes Santa Cruz | D | 2-2 |
| Chile Primera B | 2019/05/18 22:00 | Club Deportes Santa Cruz v Melipilla | W | 1-0 |
| Chile Segunda | 2017/10/18 21:59 | Club Deportes Santa Cruz v Melipilla | W | 2-1 |
| Chile Segunda | 2017/08/16 22:02 | Melipilla v Club Deportes Santa Cruz | W | 2-3 |
| Chile Segunda | 2017/04/15 22:00 | Club Deportes Santa Cruz v Melipilla | W | 1-0 |
Home History
| Chile Primera B | 2022/10/16 20:30 | San Luis Quillota v Club Deportes Santa Cruz | D | 0-0 |
| Chile Primera B | 2022/10/10 23:00 | Club Deportes Santa Cruz v Union San Felipe | W | 4-0 |
| Chile Primera B | 2022/10/03 18:30 | Deportes Recoleta v Club Deportes Santa Cruz | L | 2-1 |
| Chile Primera B | 2022/09/25 23:30 | Club Deportes Santa Cruz v Puerto Montt | L | 0-2 |
| Chile Primera B | 2022/09/12 23:30 | Deportes Copiapo v Club Deportes Santa Cruz | L | 4-2 |
| Chile Primera B | 2022/09/06 22:00 | Club Deportes Santa Cruz v Rangers de Talca | W | 2-1 |
| Chile Primera B | 2022/08/24 22:00 | Universidad de Concepcion v Club Deportes Santa Cruz | L | 3-2 |
| Chile Primera B | 2022/08/15 19:00 | Club Deportes Santa Cruz v Deportes Iquique | W | 1-0 |
Away History
| Chile Primera B | 2022/10/17 22:30 | Melipilla v Santiago Morning | W | 2-1 |
| Chile Primera B | 2022/10/09 18:00 | Magallanes v Melipilla | L | 7-0 |
| Chile Primera B | 2022/10/02 23:30 | Melipilla v CD Arturo Fernández Vial | D | 2-2 |
| Chile Primera B | 2022/09/24 15:30 | Barnechea v Melipilla | L | 4-2 |
| Chile Primera B | 2022/09/13 18:30 | Melipilla v Deportes Temuco | L | 0-1 |
| Chile Primera B | 2022/09/06 19:30 | Santiago Wanderers v Melipilla | D | 2-2 |
| Chile Primera B | 2022/08/31 00:30 | Melipilla v San Luis Quillota | L | 1-2 |
| Chile Primera B | 2022/08/25 00:30 | Cobreloa v Melipilla | L | 1-0 |