[12] Cameron Norrie 6-7,6-3,6-4 John Isner [23] 2022-02-24 00:00
Stadium: Grandstand Round: 26 Ground: Hardcourt outdoor
Head to Head
| ATP Cincinnati | 2021/08/17 17:55 | John Isner v Cameron Norrie | 4-6,7-6,6-4 |
| ATP Vienna | 2018/10/23 13:30 | Cameron Norrie v John Isner | 7-6,4-6,6-7 |
| ATP Lyon | 2018/05/24 09:00 | Cameron Norrie v John Isner | 7-6,6-4 |
Home History
| ATP Acapulco | 2022/02/23 01:35 | Cameron Norrie v Daniel Altmaier | 7-6,6-2 |
| ATP Delray Beach | 2022/02/20 20:00 | Cameron Norrie v Reilly Opelka | 7-6,7-6 |
| ATP Delray Beach | 2022/02/19 20:00 | Cameron Norrie v Tommy Paul | 6-3,6-3 |
| ATP Delray Beach | 2022/02/18 19:40 | Cameron Norrie v Sebastian Korda | 6-2,1-6,7-6 |
| ATP Delray Beach | 2022/02/17 02:55 | Cameron Norrie v Oscar Otte | 6-3,7-5 |
| ATP Rotterdam | 2022/02/11 18:30 | Cameron Norrie v Felix Auger Aliassime | 5-7,6-7 |
| ATP Rotterdam | 2022/02/09 20:30 | Cameron Norrie v Karen Khachanov | 6-4,7-6 |
| ATP Rotterdam | 2022/02/07 20:20 | Cameron Norrie v Ugo Humbert | 6-2,6-4 |
Away History
| ATP Acapulco | 2022/02/22 00:00 | Fernando Verdasco v John Isner | 5-7,7-6,6-7 |
| ATP Dallas | 2022/02/12 22:00 | John Isner v Reilly Opelka | 6-7,6-7 |
| ATP Dallas | 2022/02/12 01:00 | Vasek Pospisil v John Isner | 4-6,4-6 |
| ATP Dallas | 2022/02/10 01:00 | Kevin Anderson v John Isner | 6-7,7-6,6-7 |
| Australian Open | 2022/01/18 03:15 | Maxime Cressy v John Isner | 7-6,7-5,6-7,6-7,6-4 |
| ATP Adelaide 2 | 2022/01/12 04:30 | Thanasi Kokkinakis v John Isner | 6-7,7-6,7-6 |
| ATP Cup | 2022/01/05 23:00 | Daniel Evans v John Isner | 6-4,7-6 |
| ATP Cup | 2022/01/03 23:00 | Jan-Lennard Struff v John Isner | 7-6,4-6,7-5 |