Stadium: Orleans Arena Round: 122
Home Manager: Sam Scholl Away Manager: Lorenzo Romar
| NCAAB | 2022/01/27 08:27 | Pepperdine v San Diego | L | 56-64 |
| NCAAB | 2022/01/11 03:00 | San Diego v Pepperdine | L | 72-62 |
| NCAAB | 2021/02/27 21:00 | Pepperdine v San Diego | W | 90-84 |
| NCAAB | 2020/02/14 04:00 | San Diego v Pepperdine | W | 69-72 |
| NCAAB | 2020/01/12 03:00 | Pepperdine v San Diego | W | 85-78 |
| NCAAB | 2019/02/09 21:00 | San Diego v Pepperdine | W | 67-70 |
| NCAAB | 2019/01/12 21:00 | Pepperdine v San Diego | W | 76-71 |
| NCAAB | 2018/02/09 03:30 | San Diego v Pepperdine | L | 68-66 |
| NCAAB | 2022/02/27 01:00 | Pepperdine v BYU | L | 59-75 |
| NCAAB | 2022/02/25 03:00 | Santa Clara v Pepperdine | L | 89-73 |
| NCAAB | 2022/02/20 01:00 | Pepperdine v Portland | L | 74-77 |
| NCAAB | 2022/02/17 04:00 | Gonzaga v Pepperdine | L | 86-66 |
| NCAAB | 2022/02/13 03:00 | BYU v Pepperdine | L | 91-85 |
| NCAAB | 2022/02/11 04:00 | Pepperdine v San Francisco | L | 61-105 |
| NCAAB | 2022/02/06 01:00 | Pacific v Pepperdine | W | 64-70 |
| NCAAB | 2022/02/04 03:00 | Pepperdine v Pacific | L | 76-81 |
| NCAAB | 2022/02/26 22:00 | San Francisco v San Diego | L | 78-62 |
| NCAAB | 2022/02/25 03:00 | Saint Mary's CA v San Diego | L | 60-46 |
| NCAAB | 2022/02/17 08:27 | San Diego v Portland | L | 60-92 |
| NCAAB | 2022/02/13 02:00 | Pacific v San Diego | W | 54-60 |
| NCAAB | 2022/02/11 02:00 | San Diego v Saint Mary's CA | L | 57-86 |
| NCAAB | 2022/02/06 00:00 | Santa Clara v San Diego | L | 79-66 |
| NCAAB | 2022/02/04 02:00 | Gonzaga v San Diego | L | 92-62 |
| NCAAB | 2022/01/30 00:00 | San Diego v Loyola Marymount | W | 69-65 |