| Colombia Regional League | 2021/12/04 19:20 | Envigado FC Reserves v Molino Viejo | W | 1-0 |
| Colombia Regional League | 2021/11/16 15:00 | Envigado FC Reserves v CD Los Del Sur | W | 2-1 |
| Colombia Regional League | 2021/10/24 21:00 | Inder Girardota v Envigado FC Reserves | D | 1-1 |
| Colombia Regional League | 2021/10/06 16:00 | Independiente Sabaneta v Envigado FC Reserves | W | 0-2 |
| Colombia Regional League | 2021/08/29 17:23 | Deportivo Alexis Garcia v Envigado FC Reserves | W | 1-2 |
| Colombia Regional League | 2021/07/17 19:20 | Estudiantes de Medellin v Envigado FC Reserves | W | 0-3 |
| Colombia Regional League | 2021/06/28 15:00 | Envigado FC Reserves v Total Soccer FC | D | 0-0 |
| Colombia Regional League | 2021/06/21 13:11 | Molino Viejo v Envigado FC Reserves | W | 0-1 |
| Colombia Regional League | 2021/12/06 13:00 | CD Los Del Sur v Talento y Vida | W | 0-2 |
| Colombia Regional League | 2021/12/01 15:30 | Sellos Colombianos v Talento y Vida | L | 3-1 |
| Colombia Regional League | 2021/10/26 17:00 | Talento y Vida v Ferrovalvulas FC | L | 1-2 |
| Colombia Regional League | 2021/08/23 16:10 | Sellos Colombianos v Talento y Vida | L | 3-1 |
| Colombia Regional League | 2021/08/08 17:15 | Talento y Vida v Independiente Sabaneta | L | 1-2 |
| Colombia Regional League | 2021/07/17 15:00 | Talento y Vida v Inder Girardota | W | 2-0 |
| Colombia Regional League | 2021/03/19 16:15 | Talento y Vida v Deportivo Alexis Garcia | L | 1-2 |
| Colombia Regional League | 2021/03/16 17:51 | E.D.P IND. Medellin v Talento y Vida | L | 5-1 |