Stadium: Barclays Center Round: 124
Home Manager: Mike Young Away Manager: Brad Brownell
| NCAAB | 2022/03/05 19:00 | Virginia Tech v Clemson | W | 59-63 |
| NCAAB | 2020/12/15 23:30 | Clemson v Virginia Tech | L | 60-66 |
| NCAAB | 2020/03/05 00:00 | Clemson v Virginia Tech | L | 58-70 |
| NCAAB | 2019/11/06 00:00 | Virginia Tech v Clemson | L | 67-60 |
| NCAAB | 2019/02/09 17:00 | Virginia Tech v Clemson | W | 51-59 |
| NCAAB | 2018/02/22 00:00 | Clemson v Virginia Tech | L | 58-65 |
| NCAAB | 2017/02/22 00:00 | Clemson v Virginia Tech | L | 70-71 |
| NCAAB | 2017/01/22 23:30 | Virginia Tech v Clemson | L | 82-81 |
| NCAAB | 2022/03/08 21:30 | NC State v Clemson | W | 64-70 |
| NCAAB | 2022/03/05 19:00 | Virginia Tech v Clemson | W | 59-63 |
| NCAAB | 2022/03/03 00:00 | Georgia Tech v Clemson | W | 65-68 |
| NCAAB | 2022/02/26 20:00 | Clemson v Boston College | W | 70-60 |
| NCAAB | 2022/02/24 00:00 | Wake Forest v Clemson | W | 69-80 |
| NCAAB | 2022/02/19 20:00 | Clemson v Louisville | L | 61-70 |
| NCAAB | 2022/02/16 00:00 | Clemson v Florida State | L | 80-81 |
| NCAAB | 2022/02/13 00:00 | Notre Dame v Clemson | L | 76-61 |
| NCAAB | 2022/03/05 19:00 | Virginia Tech v Clemson | L | 59-63 |
| NCAAB | 2022/03/02 02:00 | Louisville v Virginia Tech | W | 43-75 |
| NCAAB | 2022/02/26 20:00 | Virginia Tech v Miami Florida | W | 71-70 |
| NCAAB | 2022/02/24 02:00 | Virginia Tech v Georgia Tech | W | 62-58 |
| NCAAB | 2022/02/19 21:00 | North Carolina v Virginia Tech | L | 65-57 |
| NCAAB | 2022/02/15 00:00 | Virginia v Virginia Tech | W | 53-62 |
| NCAAB | 2022/02/12 23:00 | Syracuse v Virginia Tech | W | 59-71 |
| NCAAB | 2022/02/08 00:00 | Pittsburgh v Virginia Tech | W | 47-74 |