Head to Head
| MLB | 2022/05/10 00:10 | CLE Guardians v CHI White Sox | W | 12-9 |
| MLB | 2022/04/21 17:10 | CHI White Sox v CLE Guardians | W | 3-6 |
| MLB | 2022/04/20 21:40 | CHI White Sox v CLE Guardians | W | 1-2 |
| MLB | 2022/04/20 18:10 | CHI White Sox v CLE Guardians | W | 1-11 |
| MLB Spring Training | 2022/03/19 20:05 | CLE Guardians v CHI White Sox | W | 11-2 |
| MLB | 2021/09/26 17:10 | CHI White Sox v CLE Guardians | L | 5-2 |
| MLB | 2021/09/25 23:15 | CHI White Sox v CLE Guardians | W | 0-6 |
| MLB | 2021/09/24 23:10 | CHI White Sox v CLE Guardians | L | 1-0 |
Home History
| MLB | 2022/05/10 00:10 | CLE Guardians v CHI White Sox | W | 12-9 |
| MLB | 2022/05/08 17:40 | TOR Blue Jays v CLE Guardians | W | 3-4 |
| MLB | 2022/05/07 21:40 | TOR Blue Jays v CLE Guardians | W | 2-8 |
| MLB | 2022/05/07 18:10 | TOR Blue Jays v CLE Guardians | L | 8-3 |
| MLB | 2022/05/05 22:10 | TOR Blue Jays v CLE Guardians | W | 5-6 |
| MLB | 2022/05/04 21:10 | SD Padres v CLE Guardians | W | 5-6 |
| MLB | 2022/05/04 17:10 | SD Padres v CLE Guardians | L | 5-4 |
| MLB | 2022/05/01 20:07 | CLE Guardians v OAK Athletics | W | 7-3 |
Away History
| MLB | 2022/05/10 00:10 | CLE Guardians v CHI White Sox | L | 12-9 |
| MLB | 2022/05/08 15:35 | CHI White Sox v BOS Red Sox | W | 3-2 |
| MLB | 2022/05/07 20:10 | CHI White Sox v BOS Red Sox | W | 3-1 |
| MLB | 2022/05/06 23:10 | CHI White Sox v BOS Red Sox | W | 4-2 |
| MLB | 2022/05/04 23:40 | CHI White Sox v CHI Cubs | W | 4-3 |
| MLB | 2022/05/03 23:40 | CHI White Sox v CHI Cubs | W | 3-1 |
| MLB | 2022/05/02 18:10 | LA Angels v CHI White Sox | W | 0-3 |
| MLB | 2022/05/01 18:10 | LA Angels v CHI White Sox | L | 6-5 |