[114] Sam Querrey 6-7,6-7 John Isner [23] 2022-03-13 18:00
Stadium: Stadium 2 Round: 24 Ground: Hardcourt outdoor
Head to Head
| French Open | 2021/05/31 09:00 | Sam Querrey v John Isner | 6-7,3-6,4-6 |
| ATP Acapulco | 2019/02/27 22:00 | John Isner v Sam Querrey | 6-4,6-4 |
| ATP Cincinnati | 2018/08/13 20:15 | John Isner v Sam Querrey | 4-6,7-6,6-7 |
| ATP Cincinnati | 2015/08/18 16:25 | John Isner v Sam Querrey | 3-6,6-7 |
| ATP Memphis | 2015/02/14 03:35 | John Isner v Sam Querrey | 6-7,6-7 |
Home History
| ATP Indian Wells | 2022/03/12 03:25 | Tallon Griekspoor v Sam Querrey | 7-6,2-6,4-6 |
| ATP Delray Beach | 2022/02/15 18:00 | Denis Istomin v Sam Querrey | 6-1,7-6 |
| ATP Dallas | 2022/02/07 22:00 | Kevin Anderson v Sam Querrey | 6-4,6-4 |
| Australian Open | 2022/01/17 06:35 | Sam Querrey v Lorenzo Sonego | 5-7,3-6,3-6 |
| ATP Indian Wells | 2021/10/07 18:00 | Daniel Altmaier v Sam Querrey | 6-2,6-4 |
| US Open | 2021/08/31 16:00 | Alexander Zverev v Sam Querrey | 6-4,7-5,6-2 |
| ATP Washington | 2021/08/02 23:00 | Kei Nishikori v Sam Querrey | 6-4,6-3 |
| ATP Atlanta | 2021/07/26 23:00 | Peter Gojowczyk v Sam Querrey | 4-6,7-6,7-6 |
Away History
| ATP Acapulco | 2022/02/24 00:00 | Cameron Norrie v John Isner | 6-7,6-3,6-4 |
| ATP Acapulco | 2022/02/22 00:00 | Fernando Verdasco v John Isner | 5-7,7-6,6-7 |
| ATP Dallas | 2022/02/12 22:00 | John Isner v Reilly Opelka | 6-7,6-7 |
| ATP Dallas | 2022/02/12 01:00 | Vasek Pospisil v John Isner | 4-6,4-6 |
| ATP Dallas | 2022/02/10 01:00 | Kevin Anderson v John Isner | 6-7,7-6,6-7 |
| Australian Open | 2022/01/18 03:15 | Maxime Cressy v John Isner | 7-6,7-5,6-7,6-7,6-4 |
| ATP Adelaide 2 | 2022/01/12 04:30 | Thanasi Kokkinakis v John Isner | 6-7,7-6,7-6 |
| ATP Cup | 2022/01/05 23:00 | Daniel Evans v John Isner | 6-4,7-6 |