Stadium: Bon Secours Wellness Arena Round: 122
Home Manager: Tom Izzo Away Manager: Bob McKillop
| NCAAB | 2022/03/13 17:00 | Richmond v Davidson | L | 64-62 |
| NCAAB | 2022/03/12 18:00 | St Louis v Davidson | W | 69-84 |
| NCAAB | 2022/03/11 17:00 | Fordham v Davidson | W | 56-74 |
| NCAAB | 2022/03/05 17:30 | Davidson v Dayton | L | 76-82 |
| NCAAB | 2022/03/03 00:00 | George Mason v Davidson | W | 62-73 |
| NCAAB | 2022/02/26 19:30 | Fordham v Davidson | W | 45-66 |
| NCAAB | 2022/02/24 00:00 | Davidson v Duquesne | W | 74-50 |
| NCAAB | 2022/02/19 20:30 | St Louis v Davidson | W | 58-79 |
| NCAAB | 2022/03/12 20:30 | Michigan State v Purdue | L | 70-75 |
| NCAAB | 2022/03/11 23:30 | Michigan State v Wisconsin | W | 69-63 |
| NCAAB | 2022/03/10 23:30 | Maryland v Michigan State | W | 72-76 |
| NCAAB | 2022/03/06 21:30 | Maryland v Michigan State | W | 67-77 |
| NCAAB | 2022/03/04 00:00 | Michigan State v Ohio State | L | 69-80 |
| NCAAB | 2022/03/02 01:30 | Michigan State v Michigan | L | 70-87 |
| NCAAB | 2022/02/26 17:00 | Purdue v Michigan State | W | 65-68 |
| NCAAB | 2022/02/23 00:00 | Michigan State v Iowa | L | 60-86 |