Stadium: George M. Holmes Convocation Center Round: 124
Home Manager: Dustin Kerns Away Manager: Dave Dickerson
| NCAAB | 2022/03/05 17:00 | USC Upstate v Longwood | L | 70-79 |
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | W | 62-72 |
| NCAAB | 2022/02/26 21:00 | Gardner Webb v USC Upstate | W | 70-72 |
| NCAAB | 2022/02/25 00:00 | USC Upstate v Winthrop | L | 59-89 |
| NCAAB | 2022/02/19 22:30 | USC Upstate v Charleston Southern | W | 78-73 |
| NCAAB | 2022/02/16 23:00 | Presbyterian v USC Upstate | W | 55-60 |
| NCAAB | 2022/02/12 21:00 | UNC Asheville v USC Upstate | L | 83-56 |
| NCAAB | 2022/02/11 00:00 | USC Upstate v Longwood | L | 72-85 |
| NCAAB | 2022/03/07 01:30 | Georgia State v Appalachian State | L | 71-66 |
| NCAAB | 2022/03/06 01:30 | Georgia Southern v Appalachian State | W | 60-73 |
| NCAAB | 2022/02/26 01:00 | Appalachian State v Arkansas State | L | 60-62 |
| NCAAB | 2022/02/24 00:30 | Appalachian State v Arkansas LR | W | 78-66 |
| NCAAB | 2022/02/19 21:30 | South Alabama v Appalachian State | W | 51-69 |
| NCAAB | 2022/02/17 23:30 | Troy v Appalachian State | L | 67-61 |
| NCAAB | 2022/02/12 21:00 | Georgia State v Appalachian State | L | 58-49 |
| NCAAB | 2022/02/10 23:30 | Georgia Southern v Appalachian State | W | 61-65 |