[4] Penarol 0-0 Cerro Porteno [1] 2022-05-17 22:15
Stadium: Estadio Campeon del Siglo Round: 5
Referee: Wilton Pereira Sampaio Home Manager: Mauricio Larriera Away Manager: Francisco Arce
Head to Head
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteno v Penarol | L | 1-0 |
| Club Friendly List | 2016/01/17 01:15 | Penarol v Cerro Porteno | W | 1-0 |
Home History
| Uruguay Apertura | 2022/05/13 23:30 | Plaza Colonia v Penarol | W | 0-1 |
| Uruguay Apertura | 2022/05/08 22:00 | Penarol v Montevideo Wanderers | W | 1-0 |
| Copa Libertadores | 2022/05/05 00:00 | Olimpia Asuncion v Penarol | L | 1-0 |
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteno v Penarol | L | 1-0 |
| Uruguay Apertura | 2022/04/23 22:00 | Torque v Penarol | W | 0-1 |
| Uruguay Apertura | 2022/04/16 22:00 | Cerrito v Penarol | D | 0-0 |
| Copa Libertadores | 2022/04/13 00:30 | Penarol v Olimpia Asuncion | W | 2-1 |
| Uruguay Apertura | 2022/04/09 19:00 | Penarol v Liverpool Montevideo | W | 2-1 |
Away History
| Paraguay Division Profesional | 2022/05/14 23:15 | Sol de America v Cerro Porteno | L | 2-1 |
| Paraguay Division Profesional | 2022/05/12 00:15 | Cerro Porteno v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2022/05/08 23:15 | Guarani Asuncion v Cerro Porteno | W | 1-2 |
| Copa Libertadores | 2022/05/04 22:00 | Colon v Cerro Porteno | L | 2-1 |
| Paraguay Division Profesional | 2022/04/30 23:45 | Cerro Porteno v Nacional Asuncion | W | 1-0 |
| Copa Libertadores | 2022/04/28 00:00 | Cerro Porteno v Penarol | W | 1-0 |
| Paraguay Division Profesional | 2022/04/24 21:30 | Sportivo Ameliano v Cerro Porteno | W | 0-1 |
| Paraguay Division Profesional | 2022/04/21 22:00 | Tacuary v Cerro Porteno | L | 2-0 |