[2] Colo Colo 1-2 River Plate [1] 2022-04-28 00:00
Stadium: Monumental David Arellano Round: 3
Referee: Alexis Adrian Herrera Hernandez Home Manager: Gustavo Quinteros Away Manager: Marcelo Gallardo
Home History
| Chile Primera Division | 2022/04/24 16:30 | Universidad Catolica v Colo Colo | D | 1-1 |
| Chile Primera Division | 2022/04/17 22:00 | Colo Colo v Cobresal | W | 2-1 |
| Copa Libertadores | 2022/04/13 22:00 | Colo Colo v Alianza Lima | W | 2-1 |
| Chile Primera Division | 2022/04/10 21:30 | Union Espanola v Colo Colo | L | 2-1 |
| Copa Libertadores | 2022/04/07 22:00 | Fortaleza v Colo Colo | W | 1-2 |
| Chile Primera Division | 2022/03/31 22:00 | Colo Colo v Union La Calera | W | 4-0 |
| Chile Primera Division | 2022/03/20 20:30 | Palestino v Colo Colo | W | 0-5 |
| Chile Primera Division | 2022/03/14 21:00 | CD Antofagasta v Colo Colo | W | 0-1 |
Away History
| Argentina Liga Profesional | 2022/04/24 22:00 | River Plate v Atlético Tucumán | D | 1-1 |
| Argentina Liga Profesional | 2022/04/20 22:00 | CA Talleres de Córdoba v River Plate | L | 1-0 |
| Argentina Liga Profesional | 2022/04/18 00:30 | Banfield v River Plate | W | 1-2 |
| Copa Libertadores | 2022/04/14 00:00 | River Plate v Fortaleza | W | 2-0 |
| Argentina Liga Profesional | 2022/04/10 22:00 | River Plate v Argentinos Jrs | W | 4-2 |
| Copa Libertadores | 2022/04/07 00:00 | Alianza Lima v River Plate | W | 0-1 |
| Argentina Liga Profesional | 2022/04/02 22:00 | Defensa y Justicia v River Plate | W | 1-2 |
| Argentina Liga Profesional | 2022/03/20 22:00 | River Plate v Boca Juniors | L | 0-1 |