[14] Santos Laguna Women 0-3 Club America Women [4] 2022-04-12 00:00
Stadium: Estadio TSM Corona Round: 9
Head to Head
| Mexico Liga MX Femenil | 2021/07/18 17:00 | Club America Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2021/04/06 00:00 | Santos Laguna Women v Club America Women | L | 1-2 |
| Mexico Liga MX Femenil | 2020/09/18 21:00 | Club America Women v Santos Laguna Women | L | 2-1 |
| Mexico Liga MX Femenil | 2020/01/20 21:45 | Club America Women v Santos Laguna Women | L | 3-2 |
| Mexico Liga MX Femenil | 2019/10/22 00:00 | Santos Laguna Women v Club America Women | L | 0-1 |
Home History
| Mexico Liga MX Femenil | 2022/04/01 03:00 | Santos Laguna Women v Puebla Women | D | 0-0 |
| Mexico Liga MX Femenil | 2022/03/27 16:00 | Monterrey Women v Santos Laguna Women | L | 3-1 |
| Mexico Liga MX Femenil | 2022/03/20 23:00 | Atletico San Luis Women v Santos Laguna Women | W | 2-4 |
| Mexico Liga MX Femenil | 2022/03/18 01:00 | Santos Laguna Women v Pachuca Women | L | 0-1 |
| Mexico Liga MX Femenil | 2022/03/12 18:00 | Cruz Azul Women v Santos Laguna Women | W | 2-3 |
| Mexico Liga MX Femenil | 2022/03/01 01:00 | Santos Laguna Women v Queretaro Women | L | 0-1 |
| Mexico Liga MX Femenil | 2022/02/13 16:30 | Chivas Guadalajara Women v Santos Laguna Women | L | 1-0 |
| Mexico Liga MX Femenil | 2022/02/08 01:00 | Santos Laguna Women v Leon Women | L | 1-3 |
Away History
| Mexico Liga MX Femenil | 2022/04/01 21:45 | Club America Women v Juarez FC Women | W | 2-1 |
| Mexico Liga MX Femenil | 2022/03/27 18:00 | Puebla Women v Club America Women | D | 1-1 |
| Mexico Liga MX Femenil | 2022/03/21 23:00 | Toluca Women v Club America Women | W | 0-4 |
| Mexico Liga MX Femenil | 2022/03/16 21:45 | Club America Women v Queretaro Women | W | 4-1 |
| Mexico Liga MX Femenil | 2022/03/14 03:00 | Club America Women v Chivas Guadalajara Women | L | 1-2 |
| Mexico Liga MX Femenil | 2022/02/28 21:45 | Club America Women v Mazatlan FC Women | W | 3-0 |
| Mexico Liga MX Femenil | 2022/02/11 01:00 | Leon Women v Club America Women | W | 1-4 |
| Mexico Liga MX Femenil | 2022/02/05 18:00 | Cruz Azul Women v Club America Women | W | 1-3 |