Stadium: Caesars Superdome Round: 140
Home Manager: Mike Krzyzewski Away Manager: Hubert Davis
| NCAAB | 2022/03/05 23:00 | North Carolina v Duke | W | 94-81 |
| NCAAB | 2022/02/05 23:00 | Duke v North Carolina | L | 87-67 |
| NCAAB | 2021/03/06 23:00 | Duke v North Carolina | W | 73-91 |
| NCAAB | 2021/02/06 23:00 | North Carolina v Duke | W | 91-87 |
| NCAAB | 2020/03/07 23:00 | North Carolina v Duke | L | 76-89 |
| NCAAB | 2020/02/08 23:00 | Duke v North Carolina | L | 98-96 |
| NCAAB | 2019/03/16 01:00 | Duke v North Carolina | L | 74-73 |
| NCAAB | 2019/03/09 23:00 | Duke v North Carolina | W | 70-79 |
| NCAAB | 2022/03/27 21:05 | St. Peter's v North Carolina | W | 49-69 |
| NCAAB | 2022/03/26 01:39 | North Carolina v UCLA | W | 73-66 |
| NCAAB | 2022/03/19 16:10 | North Carolina v Baylor Bears | W | 93-86 |
| NCAAB | 2022/03/17 20:30 | Marquette v North Carolina | W | 63-95 |
| NCAAB | 2022/03/12 02:30 | Virginia Tech v North Carolina | L | 72-59 |
| NCAAB | 2022/03/11 02:30 | Virginia v North Carolina | W | 43-63 |
| NCAAB | 2022/03/05 23:00 | North Carolina v Duke | W | 94-81 |
| NCAAB | 2022/03/01 00:00 | Syracuse v North Carolina | W | 79-88 |
| NCAAB | 2022/03/27 00:49 | Arkansas v Duke | W | 69-78 |
| NCAAB | 2022/03/25 01:39 | Texas Tech v Duke | W | 73-78 |
| NCAAB | 2022/03/20 21:15 | Michigan State v Duke | W | 76-85 |
| NCAAB | 2022/03/18 23:10 | CS Fullerton v Duke | W | 61-78 |
| NCAAB | 2022/03/13 01:30 | Virginia Tech v Duke | L | 82-67 |
| NCAAB | 2022/03/12 00:00 | Miami Florida v Duke | W | 76-80 |
| NCAAB | 2022/03/10 17:00 | Syracuse v Duke | W | 79-88 |
| NCAAB | 2022/03/05 23:00 | North Carolina v Duke | L | 94-81 |