| Guatemala Liga Nacional Women | 2022/02/20 01:00 | K’iche FC Women v Deportivo Mixco Women | L | 4-2 |
| Guatemala Liga Nacional Women | 2022/03/27 21:00 | Antigua GFC Women v Deportivo Mixco Women | D | 2-2 |
| Guatemala Liga Nacional Women | 2022/03/06 17:00 | Tunecas Women v Deportivo Mixco Women | L | 3-1 |
| Guatemala Liga Nacional Women | 2022/02/27 02:00 | Deportivo Mixco Women v Deportivo Colomba Women | W | 3-0 |
| Guatemala Liga Nacional Women | 2022/02/20 01:00 | K’iche FC Women v Deportivo Mixco Women | L | 4-2 |
| Guatemala Liga Nacional Women | 2022/02/14 00:00 | Deportivo Mixco Women v Antigua GFC Women | W | 3-2 |
| Guatemala Liga Nacional Women | 2022/02/07 00:00 | Deportivo Mixco Women v CSD Barcena FF Women | W | 4-0 |
| Guatemala Liga Nacional Women | 2021/11/14 16:00 | Cobaneras FC Women v Deportivo Mixco Women | L | 2-0 |
| Guatemala Liga Nacional Women | 2021/10/25 00:10 | Deportivo Mixco Women v Pares Women | W | 3-0 |
| Guatemala Liga Nacional Women | 2022/02/20 01:00 | K’iche FC Women v Deportivo Mixco Women | W | 4-2 |
| Guatemala Liga Nacional Women | 2022/02/12 21:00 | Tunecas Women v K’iche FC Women | L | 2-1 |
| Guatemala Liga Nacional Women | 2021/11/28 01:00 | Xinabajul Women v K’iche FC Women | L | 3-0 |
| Guatemala Liga Nacional Women | 2021/09/25 17:00 | Deportivo Colomba Women v K’iche FC Women | W | 1-7 |
| Guatemala Liga Nacional Women | 2021/09/12 18:00 | Tunecas Women v K’iche FC Women | L | 3-1 |
| Guatemala Liga Nacional Women | 2021/09/05 17:18 | K’iche FC Women v Gardenias de Coatepeque Women | D | 1-1 |
| Guatemala Liga Nacional Women | 2021/08/29 18:10 | Malacateco Women v K’iche FC Women | W | 0-7 |