[7] Orlando City SC II 3-5 FC Cincinnati II [20] 2022-05-29 23:00
Stadium: Osceola County Stadium Round: 1
Home History
| USA MLS Next Pro League | 2022/05/21 22:00 | Orlando City II v Inter Miami CF II | W | 6-0 |
| USA MLS Next Pro League | 2022/05/16 23:00 | Philadelphia Union II v Orlando City II | L | 1-0 |
| USA MLS Next Pro League | 2022/04/24 23:00 | Orlando City II v New England Revolution II | D | 0-0 |
| USA MLS Next Pro League | 2022/04/15 23:00 | Columbus Crew II v Orlando City II | L | 2-0 |
| USA MLS Next Pro League | 2022/04/10 21:30 | Inter Miami CF II v Orlando City II | L | 2-0 |
| USA MLS Next Pro League | 2022/04/03 22:00 | Orlando City II v New York City FC II | W | 7-6 |
| USA MLS Next Pro League | 2022/03/26 19:00 | Orlando City II v Chicago Fire II | W | 2-0 |
| USA USL League One | 2020/10/24 17:00 | Orlando City II v Greenville Triumph SC | L | 1-4 |
Away History
| USA MLS Next Pro League | 2022/05/22 21:00 | FC Cincinnati II v New England Revolution II | L | 0-1 |
| USA MLS Next Pro League | 2022/05/15 22:00 | Chicago Fire II v FC Cincinnati II | L | 3-1 |
| USA MLS Next Pro League | 2022/05/08 21:00 | FC Cincinnati II v RNY FC | L | 1-2 |
| USA MLS Next Pro League | 2022/04/30 22:00 | Toronto FC II v FC Cincinnati II | L | 4-2 |
| USA MLS Next Pro League | 2022/04/23 17:00 | FC Cincinnati II v Inter Miami CF II | L | 0-1 |
| USA MLS Next Pro League | 2022/04/17 18:00 | New England Revolution II v FC Cincinnati II | L | 3-2 |
| USA MLS Next Pro League | 2022/04/03 18:00 | FC Cincinnati II v Toronto FC II | W | 2-1 |
| USA MLS Next Pro League | 2022/03/27 18:00 | Philadelphia Union II v FC Cincinnati II | L | 2-0 |