St Louis City II 2-0 Houston Dynamo II 2022-06-05 00:00
Stadium: The Robert R. Hermann Stadium Round: 1
Home History
| USA MLS Next Pro League | 2022/05/30 00:00 | St Louis City II v The Town | L | 4-5 |
| USA MLS Next Pro League | 2022/05/23 00:00 | St Louis City II v Portland Timbers II | W | 3-1 |
| USA MLS Next Pro League | 2022/05/08 00:00 | St Louis City II v Vancouver Whitecaps II | L | 1-2 |
| USA MLS Next Pro League | 2022/04/30 01:00 | Real Monarchs SLC v St Louis City II | W | 0-2 |
| USA MLS Next Pro League | 2022/04/25 00:00 | St Louis City II v Minnesota United FC II | L | 0-4 |
| USA US Open Cup | 2022/04/20 23:30 | Louisville City FC v St Louis City II | D | 0-0 |
| USA MLS Next Pro League | 2022/04/17 00:00 | Sporting Kansas City II v St Louis City II | W | 0-1 |
| USA MLS Next Pro League | 2022/04/11 00:00 | St Louis City II v Tacoma Defiance | W | 4-3 |
Away History
| USA MLS Next Pro League | 2022/05/26 01:00 | Real Monarchs SLC v Houston Dynamo II | W | 0-1 |
| USA MLS Next Pro League | 2022/05/14 22:00 | Minnesota United FC II v Houston Dynamo II | D | 1-1 |
| USA MLS Next Pro League | 2022/05/09 01:15 | Houston Dynamo II v Colorado Rapids II | W | 2-0 |
| USA MLS Next Pro League | 2022/05/01 22:00 | Tacoma Defiance v Houston Dynamo II | L | 4-1 |
| USA MLS Next Pro League | 2022/04/23 21:15 | North Texas SC v Houston Dynamo II | W | 2-3 |
| USA MLS Next Pro League | 2022/04/17 01:00 | Houston Dynamo II v Portland Timbers II | W | 4-1 |
| USA MLS Next Pro League | 2022/04/10 23:00 | Sporting Kansas City II v Houston Dynamo II | W | 0-3 |
| USA MLS Next Pro League | 2022/04/04 01:00 | Houston Dynamo II v The Town | W | 1-0 |