Head to Head
| Malta Premier League | 2022/05/06 17:00 | Valletta v Santa Lucia FC | L | 2-1 |
| Malta Premier League | 2022/02/20 13:00 | Santa Lucia FC v Valletta | W | 2-1 |
| Malta Premier League | 2021/10/30 15:00 | Valletta v Santa Lucia FC | L | 5-3 |
| Malta Premier League | 2021/02/21 13:00 | Valletta v Santa Lucia FC | L | 1-0 |
| Malta Premier League | 2020/10/25 14:00 | Santa Lucia FC v Valletta | D | 1-1 |
| Malta Premier League | 2020/01/11 13:00 | Santa Lucia FC v Valletta | D | 2-2 |
| Malta Premier League | 2019/08/23 18:45 | Valletta v Santa Lucia FC | W | 2-3 |
Home History
| Malta Premier League | 2022/05/06 17:00 | Valletta v Santa Lucia FC | L | 2-1 |
| Malta Premier League | 2022/05/01 14:00 | Santa Lucia FC v Sliema Wanderers | L | 1-2 |
| Malta Premier League | 2022/04/24 14:00 | Mosta FC v Santa Lucia FC | D | 1-1 |
| Malta FA Trophy | 2022/04/18 17:00 | Gzira United v Santa Lucia FC | D | 0-0 |
| Malta Premier League | 2022/04/09 13:00 | Santa Lucia FC v Sirens | D | 2-2 |
| Malta Premier League | 2022/04/04 18:15 | Balzan FC v Santa Lucia FC | W | 0-3 |
| Malta FA Trophy | 2022/03/16 16:00 | St Andrews v Santa Lucia FC | W | 1-2 |
| Malta Premier League | 2022/03/11 18:00 | Balzan FC v Santa Lucia FC | W | 0-1 |
Away History
| Malta Premier League | 2022/05/06 17:00 | Valletta v Santa Lucia FC | W | 2-1 |
| Malta Premier League | 2022/04/30 13:00 | Valletta v Mosta FC | L | 2-3 |
| Malta Premier League | 2022/04/23 13:00 | Balzan FC v Valletta | D | 1-1 |
| Malta FA Trophy | 2022/04/16 12:00 | Marsaxlokk FC v Valletta | W | 0-3 |
| Malta Premier League | 2022/04/10 14:00 | Valletta v Sliema Wanderers | W | 3-1 |
| Malta Premier League | 2022/04/02 16:00 | Sirens v Valletta | W | 0-3 |
| Malta FA Trophy | 2022/03/15 19:30 | Tarxien Rainbows FC v Valletta | W | 1-5 |
| Malta Premier League | 2022/03/12 13:00 | Birkirkara v Valletta | D | 1-1 |