Head to Head
| MLB | 2022/05/24 00:10 | CLE Guardians v HOU Astros | W | 6-1 |
| MLB | 2021/07/22 00:10 | CLE Guardians v HOU Astros | W | 5-4 |
| MLB | 2021/07/21 00:10 | CLE Guardians v HOU Astros | L | 3-9 |
| MLB | 2021/07/20 00:10 | CLE Guardians v HOU Astros | L | 3-4 |
| MLB | 2021/07/04 17:10 | HOU Astros v CLE Guardians | L | 4-3 |
| MLB | 2021/07/03 23:15 | HOU Astros v CLE Guardians | L | 3-2 |
| MLB | 2021/07/02 23:10 | HOU Astros v CLE Guardians | L | 6-3 |
| MLB | 2021/07/01 23:10 | HOU Astros v CLE Guardians | L | 7-2 |
Home History
| MLB | 2022/05/24 00:10 | CLE Guardians v HOU Astros | W | 6-1 |
| MLB | 2022/05/22 17:40 | DET Tigers v CLE Guardians | L | 4-2 |
| MLB | 2022/05/20 23:10 | DET Tigers v CLE Guardians | W | 1-6 |
| MLB | 2022/05/19 17:10 | CIN Reds v CLE Guardians | L | 4-2 |
| MLB | 2022/05/17 22:10 | CIN Reds v CLE Guardians | L | 5-4 |
| MLB | 2022/05/15 18:10 | CLE Guardians v MIN Twins | L | 1-3 |
| MLB | 2022/05/14 23:10 | CLE Guardians v MIN Twins | W | 3-2 |
| MLB | 2022/05/14 00:10 | CLE Guardians v MIN Twins | L | 8-12 |
Away History
| MLB | 2022/05/24 00:10 | CLE Guardians v HOU Astros | L | 6-1 |
| MLB | 2022/05/22 18:10 | TEX Rangers v HOU Astros | W | 2-5 |
| MLB | 2022/05/21 23:10 | TEX Rangers v HOU Astros | W | 1-2 |
| MLB | 2022/05/21 00:10 | TEX Rangers v HOU Astros | L | 3-0 |
| MLB | 2022/05/20 00:10 | TEX Rangers v HOU Astros | W | 1-5 |
| MLB | 2022/05/18 22:10 | HOU Astros v BOS Red Sox | L | 1-5 |
| MLB | 2022/05/17 23:10 | HOU Astros v BOS Red Sox | W | 13-4 |
| MLB | 2022/05/16 23:10 | HOU Astros v BOS Red Sox | L | 3-6 |