[9] Defensor Sporting 0-2 Nacional De Football [5] 2022-05-14 21:00
Stadium: Estadio Luis Franzini Round: 12
Referee: Leodan Frankin Gonzalez Cabrera Home Manager: Marcelo Mendez Away Manager: Pablo Repetto
Head to Head
| Uruguay Clausura | 2021/03/08 00:45 | Nacional De Football v Defensor Sporting | L | 2-1 |
| Uruguay Torneo Intermedio | 2020/11/07 21:00 | Nacional De Football v Defensor Sporting | L | 3-0 |
| Uruguay Apertura | 2020/09/10 23:15 | Defensor Sporting v Nacional De Football | D | 1-1 |
| Uruguay Clausura | 2019/11/21 23:30 | Defensor Sporting v Nacional De Football | W | 2-1 |
| Uruguay Torneo Intermedio | 2019/07/13 21:00 | Nacional De Football v Defensor Sporting | W | 1-2 |
| Uruguay Apertura | 2019/05/19 21:30 | Nacional De Football v Defensor Sporting | L | 1-0 |
| Uruguay Clausura | 2018/08/26 21:30 | Defensor Sporting v Nacional De Football | W | 2-0 |
| Uruguay Apertura | 2018/03/10 22:00 | Nacional De Football v Defensor Sporting | L | 2-0 |
Home History
| Uruguay Apertura | 2022/05/07 16:00 | Albion FC v Defensor Sporting | W | 0-3 |
| Uruguay Apertura | 2022/04/25 23:00 | Defensor Sporting v Cerrito | D | 0-0 |
| Uruguay Apertura | 2022/04/15 23:15 | Defensor Sporting v Atletico Fenix Montevideo | W | 2-1 |
| Uruguay Apertura | 2022/04/08 22:15 | Cerro Largo v Defensor Sporting | D | 0-0 |
| Uruguay Apertura | 2022/04/03 00:00 | Defensor Sporting v CA River Plate | W | 3-2 |
| Uruguay Apertura | 2022/03/21 22:00 | Boston River v Defensor Sporting | D | 1-1 |
| Uruguay Apertura | 2022/03/12 22:00 | Defensor Sporting v Plaza Colonia | D | 0-0 |
| Uruguay Apertura | 2022/02/26 22:15 | Montevideo Wanderers v Defensor Sporting | L | 1-0 |
Away History
| Uruguay Apertura | 2022/05/09 22:30 | Nacional De Football v Atletico Fenix Montevideo | W | 1-0 |
| Copa Libertadores | 2022/05/04 00:30 | Estudiantes LP v Nacional De Football | L | 1-0 |
| Copa Libertadores | 2022/04/26 22:15 | Velez Sarsfield v Nacional De Football | W | 1-2 |
| Uruguay Apertura | 2022/04/22 23:00 | Cerro Largo v Nacional De Football | W | 0-2 |
| Uruguay Apertura | 2022/04/17 21:00 | Nacional De Football v CA River Plate | D | 1-1 |
| Copa Libertadores | 2022/04/14 00:00 | Nacional De Football v Estudiantes LP | D | 0-0 |
| Uruguay Apertura | 2022/04/10 21:30 | Boston River v Nacional De Football | W | 0-6 |
| Copa Libertadores | 2022/04/06 22:00 | Bragantino v Nacional De Football | L | 2-0 |