Southern Mississippi 34-27 Louisiana Tech 2017-10-21 23:00
Stadium: Joe Aillet Stadium Round: 1
Head to Head
| NCAAF | 2016/11/25 21:00 | Louisiana Tech v Southern Mississippi | W | 24-39 |
| NCAAF | 2015/11/28 17:00 | Louisiana Tech v Southern Mississippi | W | 24-58 |
| NCAAF | 2014/10/25 19:30 | Southern Mississippi v Louisiana Tech | L | 20-31 |
| NCAAF | 2011/09/03 12:00 | Southern Mississippi v Louisiana Tech | W | 19-17 |
| NCAAF | 2010/09/25 12:00 | Louisiana Tech v Southern Mississippi | W | 12-13 |
Home History
| NCAAF | 2017/10/14 23:00 | Southern Mississippi v UTEP | W | 24-0 |
| NCAAF | 2017/10/07 23:00 | Texas-San Antonio v Southern Mississippi | W | 29-31 |
| NCAAF | 2017/09/30 23:00 | Southern Mississippi v North Texas | L | 28-43 |
| NCAAF | 2017/09/16 23:00 | UL Monroe v Southern Mississippi | W | 17-28 |
| NCAAF | 2017/09/09 23:00 | Southern v Southern Mississippi | W | 0-45 |
| NCAAF | 2017/09/02 20:00 | Kentucky v Southern Mississippi | L | 24-17 |
| NCAAF | 2016/12/18 02:00 | Southern Mississippi v Lafayette | W | 28-21 |
| NCAAF | 2016/11/25 21:00 | Louisiana Tech v Southern Mississippi | W | 24-39 |
Away History
| NCAAF | 2017/10/07 20:00 | Louisiana Tech v UAB | L | 22-23 |
| NCAAF | 2017/09/30 23:00 | Louisiana Tech v South Alabama | W | 34-16 |
| NCAAF | 2017/09/23 19:30 | Louisiana Tech v South Carolina | L | 16-17 |
| NCAAF | 2017/09/16 23:00 | Western Kentucky v Louisiana Tech | W | 22-23 |
| NCAAF | 2017/09/09 23:30 | Louisiana Tech v Mississippi State | L | 21-57 |
| NCAAF | 2017/09/02 23:00 | Northwestern State v Louisiana Tech | W | 24-52 |
| NCAAF | 2016/12/23 21:30 | Louisiana Tech v Navy | W | 48-45 |
| NCAAF | 2016/12/03 17:00 | Louisiana Tech v Western Kentucky | L | 44-58 |