Head to Head
| MLB | 2022/05/04 17:10 | SD Padres v CLE Guardians | W | 5-4 |
| MLB Spring Training | 2022/03/27 20:10 | CLE Guardians v SD Padres | W | 1-5 |
| MLB Exhibition | 2022/03/22 20:05 | SD Padres v CLE Guardians | L | 1-6 |
| MLB Spring Training | 2021/03/28 20:05 | SD Padres v CLE Guardians | D | 3-3 |
| MLB Spring Training | 2021/03/11 20:10 | CLE Guardians v SD Padres | W | 4-5 |
| MLB Exhibition | 2020/02/26 20:10 | CLE Guardians v SD Padres | W | 0-8 |
| MLB Spring Training | 2019/03/18 20:05 | SD Padres v CLE Guardians | W | 3-1 |
| MLB Spring Training | 2019/03/04 20:10 | CLE Guardians v SD Padres | W | 0-8 |
Home History
| MLB | 2022/05/04 17:10 | SD Padres v CLE Guardians | W | 5-4 |
| MLB | 2022/05/01 17:35 | SD Padres v PIT Pirates | W | 5-2 |
| MLB | 2022/04/30 22:35 | SD Padres v PIT Pirates | L | 6-7 |
| MLB | 2022/04/29 22:35 | SD Padres v PIT Pirates | W | 7-3 |
| MLB | 2022/04/28 16:35 | SD Padres v CIN Reds | W | 7-5 |
| MLB | 2022/04/27 22:40 | SD Padres v CIN Reds | W | 8-5 |
| MLB | 2022/04/26 22:40 | SD Padres v CIN Reds | W | 9-6 |
| MLB | 2022/04/24 20:10 | LA Dodgers v SD Padres | L | 10-2 |
Away History
| MLB | 2022/05/04 17:10 | SD Padres v CLE Guardians | L | 5-4 |
| MLB | 2022/05/01 20:07 | CLE Guardians v OAK Athletics | W | 7-3 |
| MLB | 2022/04/30 20:07 | CLE Guardians v OAK Athletics | W | 3-1 |
| MLB | 2022/04/30 01:40 | CLE Guardians v OAK Athletics | W | 9-8 |
| MLB | 2022/04/28 20:07 | CLE Guardians v LA Angels | L | 1-4 |
| MLB | 2022/04/28 01:38 | CLE Guardians v LA Angels | L | 5-9 |
| MLB | 2022/04/27 01:38 | CLE Guardians v LA Angels | L | 1-4 |
| MLB | 2022/04/26 01:38 | CLE Guardians v LA Angels | L | 0-3 |