Head to Head
| NFL | 2021/10/31 17:00 | SF 49ers v CHI Bears | W | 33-22 |
| NFL | 2018/12/23 21:05 | CHI Bears v SF 49ers | L | 14-9 |
| NFL | 2017/12/03 18:00 | SF 49ers v CHI Bears | W | 15-14 |
| NFL | 2016/12/04 18:00 | SF 49ers v CHI Bears | L | 6-26 |
| NFL | 2015/12/06 18:00 | CHI Bears v SF 49ers | W | 20-26 |
| NFL | 2014/09/15 00:30 | SF 49ers v CHI Bears | L | 20-28 |
Home History
| NFL Preseason | 2022/08/26 00:15 | SF 49ers v HOU Texans | L | 0-17 |
| NFL Preseason | 2022/08/20 23:00 | SF 49ers v MIN Vikings | W | 17-7 |
| NFL Preseason | 2022/08/13 00:30 | GB Packers v SF 49ers | W | 21-28 |
| NFL | 2022/01/30 23:30 | SF 49ers v LA Rams | L | 17-20 |
| NFL | 2022/01/23 01:15 | SF 49ers v GB Packers | W | 13-10 |
| NFL | 2022/01/16 21:30 | SF 49ers v DAL Cowboys | W | 23-17 |
| NFL | 2022/01/09 21:25 | SF 49ers v LA Rams | W | 27-24 |
| NFL | 2022/01/02 21:05 | HOU Texans v SF 49ers | W | 7-23 |
Away History
| NFL Preseason | 2022/08/27 23:00 | CHI Bears v CLE Browns | W | 21-20 |
| NFL Preseason | 2022/08/19 00:00 | CHI Bears v SEA Seahawks | W | 27-11 |
| NFL Preseason | 2022/08/13 17:00 | KC Chiefs v CHI Bears | W | 14-19 |
| NFL | 2022/01/09 18:00 | CHI Bears v MIN Vikings | L | 17-31 |
| NFL | 2022/01/02 18:00 | NY Giants v CHI Bears | W | 3-29 |
| NFL | 2021/12/26 21:05 | CHI Bears v SEA Seahawks | W | 25-24 |
| NFL | 2021/12/21 01:15 | MIN Vikings v CHI Bears | L | 17-9 |
| NFL | 2021/12/13 01:20 | CHI Bears v GB Packers | L | 30-45 |