[6] Penn State 35-31 Purdue [9] 2022-09-02 00:00
Stadium: Ross-Ade Stadium Round: 1
Home Manager: Jeff Brohm Away Manager: James Franklin
Head to Head
| NCAAF | 2019/10/05 16:00 | Purdue v Penn State | W | 7-35 |
| NCAAF | 2016/10/29 16:00 | Penn State v Purdue | W | 62-24 |
| NCAAF | 2012/11/03 12:00 | Purdue v Penn State | W | 9-34 |
| NCAAF | 2011/10/15 12:00 | Penn State v Purdue | W | 23-18 |
| NCAAF | 2008/10/04 12:00 | Purdue v Penn State | W | 6-20 |
| NCAAF | 2007/11/03 12:00 | Penn State v Purdue | W | 26-19 |
| NCAAF | 2005/10/29 12:00 | Penn State v Purdue | W | 33-15 |
| NCAAF | 2004/10/09 12:00 | Penn State v Purdue | L | 13-20 |
Home History
| NCAAF Bowl Games | 2022/01/01 17:00 | Arkansas v Penn State | L | 24-10 |
| NCAAF | 2021/11/27 20:30 | Penn State v Michigan State | L | 27-30 |
| NCAAF | 2021/11/20 17:00 | Rutgers v Penn State | W | 0-28 |
| NCAAF | 2021/11/13 17:00 | Michigan v Penn State | L | 21-17 |
| NCAAF | 2021/11/06 19:30 | Penn State v Maryland | W | 31-14 |
| NCAAF | 2021/10/30 23:30 | Penn State v Ohio State | L | 24-33 |
| NCAAF | 2021/10/23 16:00 | Illinois v Penn State | L | 20-18 |
| NCAAF | 2021/10/09 20:00 | Penn State v Iowa | L | 20-23 |
Away History
| NCAAF Bowl Games | 2021/12/30 20:00 | Purdue v Tennessee | W | 48-45 |
| NCAAF | 2021/11/27 20:30 | Indiana v Purdue | W | 7-44 |
| NCAAF | 2021/11/20 17:00 | Purdue v Northwestern | W | 32-14 |
| NCAAF | 2021/11/13 20:30 | Purdue v Ohio State | L | 31-59 |
| NCAAF | 2021/11/06 19:30 | Michigan State v Purdue | W | 29-40 |
| NCAAF | 2021/10/30 19:30 | Purdue v Nebraska | W | 28-23 |
| NCAAF | 2021/10/23 19:00 | Wisconsin v Purdue | L | 30-13 |
| NCAAF | 2021/10/16 19:30 | Purdue v Iowa | W | 24-7 |