[11] Mississippi State 16-31 LSU [7] 2022-09-17 22:00
Stadium: Tiger Stadium Round: 1
Home Manager: Brian Kelly Away Manager: Mike Leach
Head to Head
| NCAAF | 2021/09/25 16:00 | LSU v Mississippi State | L | 28-25 |
| NCAAF | 2020/09/26 19:30 | Mississippi State v LSU | W | 44-34 |
| NCAAF | 2019/10/19 19:30 | LSU v Mississippi State | L | 36-13 |
| NCAAF | 2018/10/20 23:00 | Mississippi State v LSU | L | 3-19 |
| NCAAF | 2017/09/16 23:00 | LSU v Mississippi State | W | 7-37 |
| NCAAF | 2016/09/17 23:00 | Mississippi State v LSU | L | 20-23 |
| NCAAF | 2015/09/13 01:15 | Mississippi State v LSU | L | 19-21 |
| NCAAF | 2014/09/20 23:00 | LSU v Mississippi State | W | 29-34 |
Home History
| NCAAF | 2022/09/11 03:00 | Mississippi State v Arizona | W | 39-17 |
| NCAAF | 2022/09/03 23:30 | Memphis v Mississippi State | W | 23-49 |
| NCAAF Bowl Games | 2021/12/28 23:45 | Texas Tech v Mississippi State | L | 34-7 |
| NCAAF | 2021/11/26 00:30 | Mississippi v Mississippi State | L | 31-21 |
| NCAAF | 2021/11/20 17:00 | Tennessee State v Mississippi State | W | 10-55 |
| NCAAF | 2021/11/13 17:00 | Mississippi State v Auburn | W | 43-34 |
| NCAAF | 2021/11/06 20:00 | Mississippi State v Arkansas | L | 28-31 |
| NCAAF | 2021/10/30 23:00 | Kentucky v Mississippi State | W | 17-31 |
Away History
| NCAAF | 2022/09/10 23:30 | Southern v LSU | W | 17-65 |
| NCAAF | 2022/09/04 23:30 | Florida State v LSU | L | 24-23 |
| NCAAF Bowl Games | 2022/01/05 02:00 | LSU v Kansas State | L | 20-42 |
| NCAAF | 2021/11/28 00:00 | Texas A&M v LSU | W | 24-27 |
| NCAAF | 2021/11/21 02:00 | UL Monroe v LSU | W | 14-27 |
| NCAAF | 2021/11/14 00:30 | Arkansas v LSU | L | 16-13 |
| NCAAF | 2021/11/06 23:00 | LSU v Alabama | L | 14-20 |
| NCAAF | 2021/10/23 19:30 | LSU v Mississippi | L | 17-31 |