[63] Akron 0-52 Michigan State [8] 2022-09-10 20:00
Stadium: Spartan Stadium Round: 1
Home Manager: Melvin Tucker Away Manager: Joe Moorhead
Home History
| NCAAF | 2022/09/01 22:00 | St.Francis (PA) v Akron | W | 23-30 |
| NCAAF | 2021/11/27 17:00 | Akron v Toledo | L | 14-49 |
| NCAAF | 2021/11/20 17:00 | Kent State v Akron | L | 38-0 |
| NCAAF | 2021/11/10 00:00 | Akron v Western Michigan | L | 40-45 |
| NCAAF | 2021/11/02 23:00 | Ball State v Akron | L | 31-25 |
| NCAAF | 2021/10/23 19:30 | Buffalo v Akron | L | 45-10 |
| NCAAF | 2021/10/16 18:30 | Akron v Miami Ohio | L | 21-34 |
| NCAAF | 2021/10/09 16:00 | Akron v Bowling Green | W | 35-20 |
Away History
| NCAAF | 2022/09/02 23:00 | Western Michigan v Michigan State | W | 13-35 |
| NCAAF Bowl Games | 2021/12/31 00:00 | Pittsburgh v Michigan State | W | 21-31 |
| NCAAF | 2021/11/27 20:30 | Penn State v Michigan State | W | 27-30 |
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | L | 7-56 |
| NCAAF | 2021/11/13 21:00 | Maryland v Michigan State | W | 21-40 |
| NCAAF | 2021/11/06 19:30 | Michigan State v Purdue | L | 29-40 |
| NCAAF | 2021/10/30 16:00 | Michigan v Michigan State | W | 33-37 |
| NCAAF | 2021/10/16 16:00 | Michigan State v Indiana | W | 20-15 |