[5] Toledo 21-77 Ohio State [6] 2022-09-17 23:00
Stadium: Ohio Stadium Round: 1
Home Manager: Ryan Day Away Manager: Jason Candle
Head to Head
| NCAAF | 2011/09/10 12:00 | Ohio State v Toledo | L | 27-22 |
| NCAAF | 2009/09/19 12:00 | Ohio State v Toledo | L | 38-0 |
Home History
| NCAAF | 2022/09/10 23:00 | Massachusetts v Toledo | W | 10-55 |
| NCAAF | 2022/09/01 23:00 | LIU Brooklyn v Toledo | W | 0-37 |
| NCAAF Bowl Games | 2021/12/17 17:00 | Toledo v Middle Tennessee St. | L | 24-31 |
| NCAAF | 2021/11/27 17:00 | Akron v Toledo | W | 14-49 |
| NCAAF | 2021/11/17 00:00 | Toledo v Ohio | W | 35-23 |
| NCAAF | 2021/11/11 00:00 | Toledo v Bowling Green | W | 49-17 |
| NCAAF | 2021/11/02 23:30 | Eastern Michigan v Toledo | L | 52-49 |
| NCAAF | 2021/10/23 19:30 | Western Michigan v Toledo | W | 15-34 |
Away History
| NCAAF | 2022/09/10 16:00 | Arkansas State v Ohio State | W | 12-45 |
| NCAAF | 2022/09/03 23:30 | Notre Dame v Ohio State | W | 10-21 |
| NCAAF Bowl Games | 2022/01/01 22:00 | Utah v Ohio State | W | 45-48 |
| NCAAF | 2021/11/27 17:00 | Ohio State v Michigan | L | 27-42 |
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | W | 7-56 |
| NCAAF | 2021/11/13 20:30 | Purdue v Ohio State | W | 31-59 |
| NCAAF | 2021/11/06 16:00 | Ohio State v Nebraska | W | 26-17 |
| NCAAF | 2021/10/30 23:30 | Penn State v Ohio State | W | 24-33 |