| Colombia Regional League | 2022/05/25 17:00 | Sol de Oriente v Envigado FC Reserves | L | 0-2 |
| Colombia Regional League | 2022/04/02 16:16 | Independiente Sabaneta v Sol de Oriente | D | 2-2 |
| Colombia Regional League | 2022/03/30 17:13 | Sol de Oriente v CD Gallegol | D | 0-0 |
| Colombia Regional League | 2022/03/23 17:16 | E.D.P IND. Medellin v Sol de Oriente | W | 1-2 |
| Colombia Regional League | 2022/03/09 16:42 | Sol de Oriente v Molino Viejo | W | 1-0 |
| Colombia Regional League | 2021/12/07 19:23 | Sol de Oriente v Club Deportivo La Chalaca | W | 3-1 |
| Colombia Regional League | 2021/11/14 19:00 | Sol de Oriente v Aguilas Doradas Reserves | L | 1-2 |
| Colombia Regional League | 2021/10/03 19:24 | CFD La Nororiental v Sol de Oriente | W | 0-4 |
| Colombia Regional League | 2022/05/24 17:12 | Real Santuario v Politecnico J.I.C. | W | 3-0 |
| Colombia Regional League | 2022/05/10 13:15 | Real Santuario v Envigado FC Reserves | L | 1-3 |
| Colombia Regional League | 2022/04/23 17:18 | Real Santuario v FC Leones Reserves | D | 2-2 |
| Colombia Regional League | 2022/04/11 16:00 | Estudiantes de Medellin v Real Santuario | D | 1-1 |
| Colombia Regional League | 2022/03/27 13:12 | Real Santuario v Deportivo Alexis Garcia | L | 0-2 |
| Colombia Regional League | 2022/03/01 17:13 | E.D.P IND. Medellin v Real Santuario | L | 2-0 |
| Colombia Regional League | 2021/10/06 15:13 | Real Santuario v Inder Girardota | W | 5-0 |
| Colombia Primera C | 2021/09/02 17:10 | Antioquia FC v Real Santuario | W | 2-3 |