| Uruguay Reserve League | 2019/11/07 19:00 | Defensor Sporting Reserves v Danubio Reserves | L | 3-1 |
| Uruguay Reserve League | 2019/04/16 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 2-5 |
| Uruguay Reserve League | 2018/08/01 18:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-3 |
| Uruguay Reserve League | 2022/05/23 18:00 | Atletico Fenix Reserves v Danubio Reserves | L | 3-0 |
| Uruguay Reserve League | 2022/05/16 18:00 | Danubio Reserves v Cerro Largo Reserves | W | 1-0 |
| Uruguay Reserve League | 2022/05/09 18:00 | Atletico River Plate Reserves v Danubio Reserves | L | 2-1 |
| Uruguay Reserve League | 2022/05/02 18:00 | Danubio Reserves v Boston River Reserves | L | 1-2 |
| Uruguay Reserve League | 2022/04/05 19:00 | Danubio Reserves v Montevideo Wanderers Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/03/29 16:00 | Torque Reserves v Danubio Reserves | D | 2-2 |
| Uruguay Reserve League | 2022/03/22 19:00 | Danubio Reserves v Penarol Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/03/15 19:30 | Liverpool Montevideo Reserves v Danubio Reserves | L | 2-1 |
| Uruguay Reserve League | 2022/05/26 17:00 | Albion FC Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2022/05/24 17:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | L | 1-3 |
| Uruguay Reserve League | 2022/05/10 18:00 | Defensor Sporting Reserves v Cerrito Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/05/02 18:00 | Defensor Sporting Reserves v Atletico Fenix Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/04/05 19:00 | Defensor Sporting Reserves v Atletico River Plate Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/03/29 19:00 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2022/03/22 18:00 | Defensor Sporting Reserves v Plaza Colonia Reserves | W | 3-0 |
| Uruguay Reserve League | 2022/03/15 19:30 | Montevideo Wanderers Reserves v Defensor Sporting Reserves | L | 3-1 |