| Australia Victoria U21 League | 2022/03/05 01:15 | South Melbourne U21 v Melbourne Knights U21 | L | 1-0 |
| Australia Victoria U21 League | 2021/05/09 03:14 | Melbourne Knights U21 v South Melbourne U21 | D | 1-1 |
| Australia Victoria U21 League | 2022/05/28 02:15 | Avondale U21 v Melbourne Knights U21 | W | 0-2 |
| Australia Victoria U21 League | 2022/05/21 05:00 | Melbourne Knights U21 v Dandenong City U21 | D | 1-1 |
| Australia Victoria U21 League | 2022/05/14 05:00 | Melbourne Knights U21 v Port Melbourne U21 | L | 0-1 |
| Australia Victoria U21 League | 2022/05/07 06:00 | Altona Magic U21 v Melbourne Knights U21 | L | 2-1 |
| Australia Victoria U21 League | 2022/04/30 05:30 | Melbourne Knights U21 v Oakleigh Cannons U21 | L | 1-3 |
| Australia Victoria U21 League | 2022/04/23 07:00 | Dandenong Thunder U21 v Melbourne Knights U21 | L | 1-0 |
| Australia Victoria U21 League | 2022/04/16 05:00 | Melbourne Knights U21 v Eastern Lions U21 | L | 1-4 |
| Australia Victoria U21 League | 2022/04/09 05:00 | Green Gully U21 v Melbourne Knights U21 | W | 0-4 |
| Australia Victoria U21 League | 2022/05/28 03:15 | South Melbourne U21 v Bentleigh Greens U21 | W | 2-0 |
| Australia Victoria U21 League | 2022/05/22 03:00 | Heidelberg Utd U21 v South Melbourne U21 | W | 2-5 |
| Australia Victoria U21 League | 2022/05/15 02:00 | South Melbourne U21 v Avondale U21 | W | 4-3 |
| Australia Victoria U21 League | 2022/05/07 04:45 | Dandenong City U21 v South Melbourne U21 | W | 2-9 |
| Australia Victoria U21 League | 2022/05/01 02:00 | South Melbourne U21 v Port Melbourne U21 | L | 0-3 |
| Australia Victoria U21 League | 2022/04/25 06:00 | Altona Magic U21 v South Melbourne U21 | W | 1-5 |
| Australia Victoria U21 League | 2022/04/18 04:30 | Oakleigh Cannons U21 v South Melbourne U21 | W | 2-4 |
| Australia Victoria U21 League | 2022/04/09 07:00 | Dandenong Thunder U21 v South Melbourne U21 | W | 0-6 |