| Colombia Regional League | 2021/07/17 19:20 | Estudiantes de Medellin v Envigado FC Reserves | L | 0-3 |
| Colombia Regional League | 2022/05/30 19:29 | Estudiantes de Medellin v FC Leones Reserves | L | 0-2 |
| Colombia Regional League | 2022/05/24 15:00 | Medellin City FC v Estudiantes de Medellin | L | 5-2 |
| Colombia Regional League | 2022/05/09 14:00 | Lula FC v Estudiantes de Medellin | W | 2-3 |
| Colombia Regional League | 2022/04/11 16:00 | Estudiantes de Medellin v Real Santuario | D | 1-1 |
| Colombia Regional League | 2022/04/04 15:10 | Club Deportivo La Chalaca v Estudiantes de Medellin | L | 3-1 |
| Colombia Regional League | 2022/02/28 16:00 | Sellos Colombianos v Estudiantes de Medellin | L | 6-3 |
| Colombia Regional League | 2021/11/27 21:30 | CFD La Nororiental v Estudiantes de Medellin | D | 0-0 |
| Colombia Regional League | 2021/11/16 17:00 | Estudiantes de Medellin v Molino Viejo | L | 1-2 |
| Colombia Regional League | 2022/05/25 17:00 | Sol de Oriente v Envigado FC Reserves | W | 0-2 |
| Colombia Regional League | 2022/05/17 13:00 | Envigado FC Reserves v FC Leones Reserves | W | 4-0 |
| Colombia Regional League | 2022/05/10 13:15 | Real Santuario v Envigado FC Reserves | W | 1-3 |
| Colombia Regional League | 2022/04/13 13:00 | Envigado FC Reserves v Independiente Sabaneta | W | 1-0 |
| Colombia Regional League | 2022/03/21 21:32 | Molino Viejo v Envigado FC Reserves | D | 0-0 |
| Colombia Regional League | 2022/03/08 13:17 | Envigado FC Reserves v Talento y Vida | D | 0-0 |
| Colombia Regional League | 2021/12/04 19:20 | Envigado FC Reserves v Molino Viejo | W | 1-0 |
| Colombia Regional League | 2021/11/16 15:00 | Envigado FC Reserves v CD Los Del Sur | W | 2-1 |