| Colombia Regional League | 2022/06/05 21:17 | Ferrovalvulas FC v Real Santuario | L | 2-0 |
| Colombia Regional League | 2022/05/30 17:23 | Sol de Oriente v Real Santuario | L | 2-1 |
| Colombia Regional League | 2022/05/24 17:12 | Real Santuario v Politecnico J.I.C. | W | 3-0 |
| Colombia Regional League | 2022/05/10 13:15 | Real Santuario v Envigado FC Reserves | L | 1-3 |
| Colombia Regional League | 2022/04/23 17:18 | Real Santuario v FC Leones Reserves | D | 2-2 |
| Colombia Regional League | 2022/04/11 16:00 | Estudiantes de Medellin v Real Santuario | D | 1-1 |
| Colombia Regional League | 2022/03/27 13:12 | Real Santuario v Deportivo Alexis Garcia | L | 0-2 |
| Colombia Regional League | 2022/03/01 17:13 | E.D.P IND. Medellin v Real Santuario | L | 2-0 |
| Colombia Regional League | 2022/05/09 16:30 | CD Gallegol v Total Soccer FC | L | 3-1 |
| Colombia Regional League | 2022/05/04 16:00 | Total Soccer FC v E.D.P IND. Medellin | - | View |
| Colombia Regional League | 2022/04/09 17:24 | Total Soccer FC v Talento y Vida | W | 2-1 |
| Colombia Regional League | 2022/03/28 14:00 | Total Soccer FC v Lula FC | L | 2-3 |
| Colombia Regional League | 2021/12/22 18:44 | Total Soccer FC v Aguilas Doradas Reserves | L | 0-1 |
| Colombia Regional League | 2021/11/29 17:00 | Ferrovalvulas FC v Total Soccer FC | W | 0-6 |
| Colombia Regional League | 2021/09/21 17:00 | Politecnico J.I.C. v Total Soccer FC | W | 3-5 |
| Colombia Regional League | 2021/07/17 19:29 | Total Soccer FC v CFD La Nororiental | W | 1-0 |