[8] Middle Tennessee 24-40 Louisiana Tech [7] 2022-11-05 19:00
Stadium: Joe Aillet Stadium Round: 1
Home Manager: Sonny Cumbie Away Manager: Rick Stockstill
Head to Head
| NCAAF | 2016/09/24 23:00 | Louisiana Tech v Middle Tennessee St. | W | 34-38 |
| NCAAF | 2015/10/24 19:30 | Louisiana Tech v Middle Tennessee St. | L | 45-16 |
| NCAAF | 2000/10/07 12:00 | Middle Tennessee St. v Louisiana Tech | W | 49-21 |
Home History
| NCAAF | 2022/10/30 01:00 | Middle Tennessee St. v UTEP | W | 24-13 |
| NCAAF | 2022/10/15 19:30 | Western Kentucky v Middle Tennessee St. | L | 35-17 |
| NCAAF | 2022/10/08 19:30 | Middle Tennessee St. v UAB | L | 14-41 |
| NCAAF | 2022/09/30 23:30 | Texas-San Antonio v Middle Tennessee St. | L | 45-30 |
| NCAAF | 2022/09/24 19:30 | Middle Tennessee St. v Miami Florida | W | 45-31 |
| NCAAF | 2022/09/17 23:00 | Tennessee State v Middle Tennessee St. | W | 6-49 |
| NCAAF | 2022/09/10 20:00 | Middle Tennessee St. v Colorado State | W | 34-19 |
| NCAAF | 2022/09/03 22:00 | Middle Tennessee St. v James Madison | L | 7-44 |
Away History
| NCAAF | 2022/10/29 00:00 | Louisiana Tech v Florida Intl | L | 34-42 |
| NCAAF | 2022/10/22 19:00 | Rice v Louisiana Tech | L | 42-41 |
| NCAAF | 2022/10/15 20:00 | Louisiana Tech v North Texas | L | 27-47 |
| NCAAF | 2022/10/08 23:00 | UTEP v Louisiana Tech | W | 31-41 |
| NCAAF | 2022/09/24 23:00 | Louisiana Tech v South Alabama | L | 14-38 |
| NCAAF | 2022/09/18 00:00 | Louisiana Tech v Clemson | L | 20-48 |
| NCAAF | 2022/09/10 23:00 | Stephen F. Austin v Louisiana Tech | W | 17-52 |
| NCAAF | 2022/09/02 00:00 | Louisiana Tech v Missouri | L | 24-52 |