Old Dominion 21-39 East Carolina 2022-09-10 22:00
Stadium: Bagwell Field at Dowdy-Ficklen Stadium Round: 1
Home Manager: Mike Houston Away Manager: Ricky Rahne
Head to Head
| NCAAF | 2019/09/28 22:00 | East Carolina v Old Dominion | L | 24-21 |
| NCAAF | 2018/09/29 19:30 | Old Dominion v East Carolina | L | 35-37 |
Home History
| NCAAF | 2022/09/02 23:00 | Virginia Tech v Old Dominion | W | 17-20 |
| NCAAF Bowl Games | 2021/12/20 19:30 | Tulsa v Old Dominion | L | 30-17 |
| NCAAF | 2021/11/27 19:00 | Charlotte v Old Dominion | W | 34-56 |
| NCAAF | 2021/11/20 20:30 | Old Dominion v Middle Tennessee St. | W | 24-17 |
| NCAAF | 2021/11/13 20:30 | Florida Atlantic v Old Dominion | W | 16-30 |
| NCAAF | 2021/11/06 23:00 | Old Dominion v Florida Intl | W | 47-24 |
| NCAAF | 2021/10/30 19:30 | Louisiana Tech v Old Dominion | W | 20-23 |
| NCAAF | 2021/10/16 19:30 | Western Kentucky v Old Dominion | L | 43-20 |
Away History
| NCAAF | 2022/09/03 16:00 | NC State v East Carolina | L | 21-20 |
| NCAAF | 2021/11/26 20:30 | Cincinnati v East Carolina | L | 35-13 |
| NCAAF | 2021/11/20 20:30 | East Carolina v Navy | W | 38-35 |
| NCAAF | 2021/11/13 17:00 | East Carolina v Memphis | W | 30-29 |
| NCAAF | 2021/11/06 19:00 | Temple v East Carolina | W | 3-45 |
| NCAAF | 2021/10/28 23:30 | South Florida v East Carolina | W | 14-29 |
| NCAAF | 2021/10/24 01:20 | East Carolina v Houston | L | 24-31 |
| NCAAF | 2021/10/09 22:00 | East Carolina v Central Florida | L | 16-20 |