[1] Buffalo 27-31 Central Michigan [12] 2022-11-10 00:00
Stadium: Kelly/Shorts Stadium Round: 1
Home Manager: Jim McElwain Away Manager: Maurice Linguist
Head to Head
| NCAAF | 2019/10/26 19:30 | Central Michigan v Buffalo | W | 20-43 |
| NCAAF | 2018/10/06 16:00 | Buffalo v Central Michigan | W | 34-24 |
| NCAAF | 2015/10/17 17:00 | Central Michigan v Buffalo | L | 51-14 |
| NCAAF | 2014/10/25 19:30 | Buffalo v Central Michigan | L | 14-20 |
| NCAAF | 2008/09/27 12:00 | Central Michigan v Buffalo | L | 27-25 |
| NCAAF | 2006/11/24 12:00 | Buffalo v Central Michigan | L | 28-55 |
| NCAAF | 2004/11/13 12:00 | Buffalo v Central Michigan | W | 36-6 |
| NCAAF | 2001/09/29 12:00 | Buffalo v Central Michigan | L | 8-16 |
Home History
| NCAAF | 2022/11/01 23:30 | Buffalo v Ohio | L | 24-45 |
| NCAAF | 2022/10/22 17:00 | Toledo v Buffalo | W | 27-34 |
| NCAAF | 2022/10/15 17:00 | Buffalo v Massachusetts | W | 34-7 |
| NCAAF | 2022/10/08 16:00 | Buffalo v Bowling Green | W | 38-7 |
| NCAAF | 2022/10/01 19:30 | Miami Ohio v Buffalo | W | 20-24 |
| NCAAF | 2022/09/24 16:00 | Buffalo v Eastern Michigan | W | 50-31 |
| NCAAF | 2022/09/17 17:00 | Buffalo v Coastal Carolina | L | 26-38 |
| NCAAF | 2022/09/10 22:00 | Holy Cross v Buffalo | L | 37-31 |
Away History
| NCAAF | 2022/11/02 23:00 | Central Michigan v Northern Illinois | W | 35-22 |
| NCAAF | 2022/10/22 17:00 | Bowling Green v Central Michigan | L | 34-18 |
| NCAAF | 2022/10/15 16:00 | Central Michigan v Akron | W | 28-21 |
| NCAAF | 2022/10/08 19:30 | Ball State v Central Michigan | L | 17-16 |
| NCAAF | 2022/10/01 19:30 | Central Michigan v Toledo | L | 17-38 |
| NCAAF | 2022/09/24 16:00 | Central Michigan v Penn State | L | 14-33 |
| NCAAF | 2022/09/17 17:00 | Bucknell v Central Michigan | W | 0-41 |
| NCAAF | 2022/09/10 17:00 | South Alabama v Central Michigan | L | 38-24 |