[3] Toledo 52-32 Northern Illinois [8] 2022-10-08 19:30
Stadium: Brigham Field at Huskie Stadium Round: 1
Home Manager: Thomas Hammock Away Manager: Jason Candle
Head to Head
| NCAAF | 2021/10/09 16:00 | Northern Illinois v Toledo | L | 22-20 |
| NCAAF | 2020/12/05 17:00 | Toledo v Northern Illinois | W | 41-24 |
| NCAAF | 2019/11/14 01:00 | Northern Illinois v Toledo | L | 31-28 |
| NCAAF | 2018/11/08 01:00 | Toledo v Northern Illinois | L | 15-38 |
| NCAAF | 2017/11/02 22:00 | Northern Illinois v Toledo | W | 17-27 |
| NCAAF | 2016/11/10 01:00 | Toledo v Northern Illinois | W | 31-24 |
| NCAAF | 2015/11/04 01:00 | Toledo v Northern Illinois | L | 27-32 |
| NCAAF | 2014/11/12 01:00 | Northern Illinois v Toledo | L | 27-24 |
Home History
| NCAAF | 2022/10/01 19:30 | Central Michigan v Toledo | W | 17-38 |
| NCAAF | 2022/09/24 19:30 | Toledo v San Diego State | L | 14-17 |
| NCAAF | 2022/09/17 23:00 | Toledo v Ohio State | L | 21-77 |
| NCAAF | 2022/09/10 23:00 | Massachusetts v Toledo | W | 10-55 |
| NCAAF | 2022/09/01 23:00 | LIU Brooklyn v Toledo | W | 0-37 |
| NCAAF Bowl Games | 2021/12/17 17:00 | Toledo v Middle Tennessee St. | L | 24-31 |
| NCAAF | 2021/11/27 17:00 | Akron v Toledo | W | 14-49 |
| NCAAF | 2021/11/17 00:00 | Toledo v Ohio | W | 35-23 |
Away History
| NCAAF | 2022/10/01 18:00 | Northern Illinois v Ball State | L | 38-44 |
| NCAAF | 2022/09/24 23:00 | Northern Illinois v Kentucky | L | 23-31 |
| NCAAF | 2022/09/17 19:30 | Vanderbilt v Northern Illinois | L | 38-28 |
| NCAAF | 2022/09/10 23:00 | Northern Illinois v Tulsa | L | 35-38 |
| NCAAF | 2022/09/02 00:00 | Eastern Illinois v Northern Illinois | W | 27-34 |
| NCAAF Bowl Games | 2021/12/17 23:00 | Coastal Carolina v Northern Illinois | L | 47-41 |
| NCAAF | 2021/12/04 17:00 | Kent State v Northern Illinois | W | 23-41 |
| NCAAF | 2021/11/24 00:00 | Western Michigan v Northern Illinois | L | 42-21 |