[9] Eastern Michigan 21-49 UL Lafayette [56] 2022-09-10 23:00
Stadium: Cajun Field Round: 1
Home Manager: Michael Desormeaux Away Manager: Chris Creighton
Head to Head
| NCAAF | 2006/09/30 12:00 | Lafayette v Eastern Michigan | L | 33-14 |
| NCAAF | 2005/09/10 12:00 | Eastern Michigan v Lafayette | W | 31-10 |
Home History
| NCAAF | 2022/09/02 23:00 | Eastern Kentucky v Eastern Michigan | W | 34-42 |
| NCAAF Bowl Games | 2021/12/18 22:45 | Eastern Michigan v Liberty | L | 20-56 |
| NCAAF | 2021/11/26 17:00 | Eastern Michigan v Central Michigan | L | 10-31 |
| NCAAF | 2021/11/17 00:30 | Western Michigan v Eastern Michigan | W | 21-22 |
| NCAAF | 2021/11/10 01:00 | Ohio v Eastern Michigan | L | 34-26 |
| NCAAF | 2021/11/02 23:30 | Eastern Michigan v Toledo | W | 52-49 |
| NCAAF | 2021/10/23 16:00 | Eastern Michigan v Bowling Green | W | 55-24 |
| NCAAF | 2021/10/16 18:00 | Ball State v Eastern Michigan | L | 38-31 |
Away History
| NCAAF | 2022/09/10 18:00 | Lafayette v Temple | L | 14-30 |
| NCAAF | 2022/09/03 23:00 | SE Louisiana v Lafayette | W | 7-24 |
| NCAAF | 2022/09/03 16:30 | Sacred Heart v Lafayette | W | 0-6 |
| NCAAF Bowl Games | 2021/12/19 02:15 | Marshall v Lafayette | W | 21-36 |
| NCAAF | 2021/12/04 20:30 | Appalachian St v Lafayette | W | 16-24 |
| NCAAF | 2021/11/27 21:00 | UL Monroe v Lafayette | W | 16-21 |
| NCAAF | 2021/11/20 21:00 | Lafayette v Liberty | W | 42-14 |
| NCAAF | 2021/11/20 17:00 | Lafayette v Lehigh | L | 10-17 |