| Uruguay Reserve League | 2022/06/06 18:00 | Atletico Fenix Reserves v Rentistas Reserves | D | 0-0 |
| Uruguay Reserve League | 2022/05/31 18:00 | Rentistas Reserves v Cerro Largo Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/05/24 13:00 | Atletico River Plate Reserves v Rentistas Reserves | L | 2-1 |
| Uruguay Reserve League | 2022/05/19 18:00 | Rentistas Reserves v Boston River Reserves | W | 3-2 |
| Uruguay Reserve League | 2022/05/10 13:30 | Plaza Colonia Reserves v Rentistas Reserves | W | 1-2 |
| Uruguay Reserve League | 2022/05/02 18:00 | Rentistas Reserves v Montevideo Wanderers Reserves | L | 0-1 |
| Uruguay Reserve League | 2022/04/05 19:00 | Rentistas Reserves v Penarol Reserves | D | 1-1 |
| Uruguay Reserve League | 2022/03/28 19:00 | Liverpool Montevideo Reserves v Rentistas Reserves | L | 3-2 |
| Uruguay Reserve League | 2022/06/06 18:00 | Defensor Sporting Reserves v Deportivo Maldonado Reserves | D | 1-1 |
| Uruguay Reserve League | 2022/05/31 18:00 | Danubio Reserves v Defensor Sporting Reserves | W | 0-3 |
| Uruguay Reserve League | 2022/05/26 17:00 | Albion FC Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2022/05/24 17:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | L | 1-3 |
| Uruguay Reserve League | 2022/05/10 18:00 | Defensor Sporting Reserves v Cerrito Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/05/02 18:00 | Defensor Sporting Reserves v Atletico Fenix Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/04/05 19:00 | Defensor Sporting Reserves v Atletico River Plate Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/03/29 19:00 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |