[18] Wolverhampton 1-0 Southampton [9] 2022-09-03 14:00
Stadium: Molineux Stadium Round: 6
Referee: John Brooks Home Manager: Bruno Lage Away Manager: Ralph Hasenhuttl
Head to Head
| England Premier League | 2022/01/15 15:00 | Wolverhampton v Southampton | W | 3-1 |
| England Premier League | 2021/09/26 13:00 | Southampton v Wolverhampton | W | 0-1 |
| England Premier League | 2021/02/14 12:00 | Southampton v Wolverhampton | W | 1-2 |
| England FA Cup | 2021/02/11 17:30 | Wolverhampton v Southampton | L | 0-2 |
| England Premier League | 2020/11/23 20:00 | Wolverhampton v Southampton | D | 1-1 |
| England Premier League | 2020/01/18 15:00 | Southampton v Wolverhampton | W | 2-3 |
| England Premier League | 2019/10/19 14:00 | Wolverhampton v Southampton | D | 1-1 |
| England Premier League | 2019/04/13 14:00 | Southampton v Wolverhampton | L | 3-1 |
Home History
| England Premier League | 2022/08/31 18:30 | Bournemouth v Wolverhampton | D | 0-0 |
| England Premier League | 2022/08/28 13:00 | Wolverhampton v Newcastle | D | 1-1 |
| England EFL Cup | 2022/08/23 18:45 | Wolverhampton v Preston | W | 2-1 |
| England Premier League | 2022/08/20 11:30 | Tottenham v Wolverhampton | L | 1-0 |
| England Premier League | 2022/08/13 14:00 | Wolverhampton v Fulham | D | 0-0 |
| England Premier League | 2022/08/06 14:00 | Leeds v Wolverhampton | L | 2-1 |
| Elite Club Friendlies | 2022/07/31 17:45 | SC Farense v Wolverhampton | D | 1-1 |
| Elite Club Friendlies | 2022/07/30 17:45 | Sporting v Wolverhampton | D | 1-1 |
Away History
| England Premier League | 2022/08/30 18:45 | Southampton v Chelsea | W | 2-1 |
| England Premier League | 2022/08/27 11:30 | Southampton v Man Utd | L | 0-1 |
| England EFL Cup | 2022/08/23 18:45 | Cambridge Utd v Southampton | W | 0-3 |
| England Premier League | 2022/08/20 14:00 | Leicester v Southampton | W | 1-2 |
| England Premier League | 2022/08/13 14:00 | Southampton v Leeds | D | 2-2 |
| England Premier League | 2022/08/06 14:00 | Tottenham v Southampton | L | 4-1 |
| Elite Club Friendlies | 2022/07/30 14:00 | Southampton v Villarreal | L | 1-2 |
| Elite Club Friendlies | 2022/07/27 18:45 | Southampton v Monaco | W | 3-1 |