Head to Head
| Mexico U20 League | 2022/03/18 15:00 | Puebla U20 v Santos Laguna U20 | L | 0-1 |
| Mexico U20 League | 2021/09/19 16:00 | Santos Laguna U20 v Puebla U20 | L | 4-2 |
| Mexico U20 League | 2021/05/02 16:00 | Santos Laguna U20 v Puebla U20 | W | 2-3 |
| Mexico U20 League | 2020/10/02 14:00 | Puebla U20 v Santos Laguna U20 | W | 2-1 |
| Mexico U20 League | 2020/02/07 18:00 | Puebla U20 v Santos Laguna U20 | L | 1-3 |
| Mexico U20 League | 2019/08/11 16:00 | Santos Laguna U20 v Puebla U20 | L | 5-2 |
| Mexico U20 League | 2019/01/18 18:00 | Puebla U20 v Santos Laguna U20 | D | 1-1 |
| Mexico U20 League | 2018/09/08 16:30 | Santos Laguna U20 v Puebla U20 | W | 2-3 |
Home History
| Mexico U20 League | 2022/07/01 14:00 | Mazatlan FC U20 v Puebla U20 | W | 0-2 |
| Mexico U20 League | 2022/04/29 15:00 | Mazatlan FC U20 v Puebla U20 | L | 4-1 |
| Mexico U20 League | 2022/04/22 14:00 | Puebla U20 v Necaxa U20 | L | 1-3 |
| Mexico U20 League | 2022/04/19 14:30 | Pachuca U20 v Puebla U20 | D | 2-2 |
| Mexico U20 League | 2022/04/16 14:00 | Leon U20 v Puebla U20 | L | 4-1 |
| Mexico U20 League | 2022/04/08 14:00 | Puebla U20 v Unam Pumas U20 | D | 2-2 |
| Mexico U20 League | 2022/04/03 14:00 | Toluca U20 v Puebla U20 | L | 2-0 |
| Mexico U20 League | 2022/03/18 15:00 | Puebla U20 v Santos Laguna U20 | L | 0-1 |
Away History
| Mexico U20 League | 2022/07/05 16:00 | Santos Laguna U20 v Chivas Guadalajara U20 | W | 1-0 |
| Mexico U20 League | 2022/05/08 14:00 | Leon U20 v Santos Laguna U20 | L | 5-2 |
| Mexico U20 League | 2022/05/05 16:00 | Santos Laguna U20 v Leon U20 | W | 1-0 |
| Mexico U20 League | 2022/05/01 14:00 | Atletico San Luis U20 v Santos Laguna U20 | D | 2-2 |
| Mexico U20 League | 2022/04/24 16:00 | Santos Laguna U20 v Leon U20 | L | 0-3 |
| Mexico U20 League | 2022/04/19 15:00 | Mazatlan FC U20 v Santos Laguna U20 | W | 1-2 |
| Mexico U20 League | 2022/04/16 16:00 | Santos Laguna U20 v Queretaro U20 | D | 2-2 |
| Mexico U20 League | 2022/04/03 16:00 | Santos Laguna U20 v Pachuca U20 | W | 1-0 |