[17] Tranmere 2-0 Colchester [18] 2022-08-27 14:00
Stadium: Prenton Park Round: 6
Referee: Rebecca Welch Home Manager: Micky Mellon Away Manager: Wayne Brown
Head to Head
| England League 2 | 2022/03/26 15:00 | Colchester v Tranmere | L | 1-0 |
| England League 2 | 2021/10/08 18:45 | Tranmere v Colchester | W | 2-0 |
| England League 2 | 2021/05/08 14:00 | Tranmere v Colchester | D | 0-0 |
| England League 2 | 2021/03/23 19:00 | Colchester v Tranmere | D | 2-2 |
| England League 2 | 2019/03/23 15:00 | Colchester v Tranmere | W | 0-2 |
| England League 2 | 2018/09/08 14:00 | Tranmere v Colchester | D | 1-1 |
Home History
| England EFL Cup | 2022/08/24 18:45 | Tranmere v Newcastle | L | 1-2 |
| England League 2 | 2022/08/20 14:00 | Newport County v Tranmere | L | 2-1 |
| England League 2 | 2022/08/16 18:45 | Hartlepool v Tranmere | D | 0-0 |
| England League 2 | 2022/08/13 14:00 | Tranmere v Gillingham | W | 3-0 |
| England EFL Cup | 2022/08/09 18:45 | Accrington Stanley v Tranmere | D | 2-2 |
| England League 2 | 2022/08/06 14:00 | Mansfield v Tranmere | L | 1-0 |
| England League 2 | 2022/07/30 14:00 | Tranmere v Stevenage | L | 1-2 |
| Club Friendly List | 2022/07/23 11:00 | Tranmere v Huddersfield | L | 1-4 |
Away History
| England EFL Cup | 2022/08/23 18:45 | Colchester v Brentford | L | 0-2 |
| England League 2 | 2022/08/20 14:00 | Colchester v Leyton Orient | L | 1-3 |
| England League 2 | 2022/08/16 18:45 | Colchester v Bradford | W | 1-0 |
| England League 2 | 2022/08/13 14:00 | Stockport v Colchester | L | 1-0 |
| England EFL Cup | 2022/08/09 18:45 | Ipswich v Colchester | W | 0-1 |
| England League 2 | 2022/08/06 14:00 | Colchester v Carlisle | D | 1-1 |
| England League 2 | 2022/07/30 14:00 | Northampton v Colchester | L | 3-2 |
| Club Friendly List | 2022/07/23 14:00 | Ebbsfleet United v Colchester | D | 2-2 |