UL Lafayette 22-50 Mississippi 2017-11-11 17:00
Stadium: Vaught-Hemingway Stadium Round: 1
Home Manager: Matt Luke Away Manager: Mark Hudspeth
Head to Head
| NCAAF | 2014/09/13 20:00 | Mississippi v Lafayette | L | 56-15 |
| NCAAF | 2010/11/06 12:00 | Mississippi v Lafayette | L | 43-21 |
Home History
| NCAAF | 2017/11/04 20:00 | Lafayette v South Alabama | W | 19-14 |
| NCAAF | 2017/11/04 18:00 | Georgetown v Lafayette | W | 0-7 |
| NCAAF | 2017/10/21 19:30 | Lafayette v Bucknell | L | 7-13 |
| NCAAF | 2017/10/19 23:30 | Lafayette v Arkansas State | L | 3-47 |
| NCAAF | 2017/10/14 16:00 | Harvard v Lafayette | L | 38-10 |
| NCAAF | 2017/10/12 23:30 | Texas State v Lafayette | W | 7-24 |
| NCAAF | 2017/10/07 21:00 | Lafayette v Idaho | W | 21-16 |
| NCAAF | 2017/10/07 19:30 | Lafayette v Fordham | W | 14-10 |
Away History
| NCAAF | 2017/11/04 20:00 | Mississippi v Kentucky | W | 37-34 |
| NCAAF | 2017/10/28 16:00 | Arkansas v Mississippi | L | 38-37 |
| NCAAF | 2017/10/21 23:15 | LSU v Mississippi | L | 40-24 |
| NCAAF | 2017/10/14 19:30 | Vanderbilt v Mississippi | W | 35-57 |
| NCAAF | 2017/10/07 16:00 | Mississippi v Auburn | L | 23-44 |
| NCAAF | 2017/10/01 01:00 | Mississippi v Alabama | L | 3-66 |
| NCAAF | 2017/09/17 02:30 | Mississippi v California | L | 16-27 |
| NCAAF | 2017/09/09 16:00 | Tennessee Martin v Mississippi | W | 23-45 |