| Australia Victoria U21 League | 2022/04/02 04:00 | Melbourne Knights U21 v Hume City U21 | L | 1-0 |
| Australia Victoria U21 League | 2021/06/19 09:45 | Hume City U21 v Melbourne Knights U21 | L | 0-1 |
| Australia Victoria U21 League | 2021/03/21 04:00 | Melbourne Knights U21 v Hume City U21 | D | 2-2 |
| Australia Victoria U21 League | 2022/06/24 08:15 | Bentleigh Greens U21 v Hume City U21 | L | 1-0 |
| Australia Victoria U21 League | 2022/06/18 06:00 | Hume City U21 v South Melbourne U21 | D | 1-1 |
| Australia Victoria U21 League | 2022/06/11 02:15 | Avondale U21 v Hume City U21 | W | 1-2 |
| Australia Victoria U21 League | 2022/06/04 06:00 | Hume City U21 v Dandenong City U21 | W | 4-0 |
| Australia Victoria U21 League | 2022/05/28 09:30 | Port Melbourne U21 v Hume City U21 | W | 1-2 |
| Australia Victoria U21 League | 2022/05/21 06:00 | Hume City U21 v Altona Magic U21 | W | 2-1 |
| Australia Victoria U21 League | 2022/05/14 06:00 | Hume City U21 v Oakleigh Cannons U21 | D | 0-0 |
| Australia Victoria U21 League | 2022/05/07 07:00 | Dandenong Thunder U21 v Hume City U21 | L | 2-1 |
| Australia Victoria U21 League | 2022/06/25 05:00 | Melbourne Knights U21 v St Albans Saints U21 | D | 1-1 |
| Australia Victoria U21 League | 2022/06/19 03:00 | Heidelberg Utd U21 v Melbourne Knights U21 | W | 1-4 |
| Australia Victoria U21 League | 2022/06/10 08:15 | Bentleigh Greens U21 v Melbourne Knights U21 | L | 3-2 |
| Australia Victoria U21 League | 2022/06/04 05:00 | Melbourne Knights U21 v South Melbourne U21 | L | 2-4 |
| Australia Victoria U21 League | 2022/05/28 02:15 | Avondale U21 v Melbourne Knights U21 | W | 0-2 |
| Australia Victoria U21 League | 2022/05/21 05:00 | Melbourne Knights U21 v Dandenong City U21 | D | 1-1 |
| Australia Victoria U21 League | 2022/05/14 05:00 | Melbourne Knights U21 v Port Melbourne U21 | L | 0-1 |
| Australia Victoria U21 League | 2022/05/07 06:00 | Altona Magic U21 v Melbourne Knights U21 | L | 2-1 |